Results 181 to 190 of about 248,022 (286)

Ferric derisomaltose augments intrinsic skeletal muscle electron transport chain activity in heart failure: A FERRIC‐HF II molecular substudy

open access: yesEuropean Journal of Heart Failure, EarlyView.
FERRIC‐HF II molecular substudy. FDI, ferric derisomaltose. Aims Skeletal muscle energetic augmentation might be a mechanism via which intravenous iron improves symptoms in heart failure, but no direct measurement of intrinsic mitochondrial function has been performed to support this notion.
Mohamad F. Barakat   +16 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Beyond Methane Oxidation: The Protein Landscape of ANME-2a Reveals an Integrated System for Diazotrophy and Membrane Fortification. [PDF]

open access: yesEnviron Microbiol Rep
Silva SSE   +6 more
europepmc   +1 more source

Hypolipidemic and Antioxidant Activities of Leptadenia hastata (Perse) Decne. Leaf and Syzygium aromaticum L. Bud Combination: In Vivo, In Vitro, and In Silico Evaluation

open access: yesFood Chemistry International, EarlyView.
Combination of the Leptadenia hastata leaf and the Syzygium aromaticum bud demonstrated hypolipidemic and antioxidant activities in a hyperlipidemic rat model. Combination of the two plants inhibited HMG‐CoA reductase activity, and the docking analysis revealed interacted well and formed binding complexes within the binding pocket of the enzyme ...
Farida Salisu Dabo   +7 more
wiley   +1 more source

Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis

open access: hybrid
Abigail Strefeler   +8 more
openalex   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

open access: yesFood Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li   +8 more
wiley   +1 more source

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