Results 211 to 220 of about 248,704 (239)
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Biochimica et Biophysica Acta (BBA) - General Subjects, 1961
Abstract An improved procedure for the chemical synthesis of coenzyme A by anhydride-anion exchange is described. A mixture of the 2′,5′- and 3′,5′-diphosphastes of adenosine is treated with diphenylphosphorochloridate to give P 1 -adenosine (2′3′-cyclic phosphate)-5′- P 2 -diphenylpyrophosphate quantitatively. This is then treated with pantethine
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Abstract An improved procedure for the chemical synthesis of coenzyme A by anhydride-anion exchange is described. A mixture of the 2′,5′- and 3′,5′-diphosphastes of adenosine is treated with diphenylphosphorochloridate to give P 1 -adenosine (2′3′-cyclic phosphate)-5′- P 2 -diphenylpyrophosphate quantitatively. This is then treated with pantethine
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Biochimie, 2002
Coenzymes are small organic molecules that supply a varied set of reactive groups to protein enzymes, thereby diversifying catalysis beyond the chemistries of amino acid sidechains. As RNA structures begin with a more limited chemical diversity than proteins, it seems likely that RNA enzymes would also use functional groups from other molecules to ...
Vasant Jadhav, Michael Yarus
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Coenzymes are small organic molecules that supply a varied set of reactive groups to protein enzymes, thereby diversifying catalysis beyond the chemistries of amino acid sidechains. As RNA structures begin with a more limited chemical diversity than proteins, it seems likely that RNA enzymes would also use functional groups from other molecules to ...
Vasant Jadhav, Michael Yarus
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1965
Publisher Summary This chapter provides an overview of coenzymes and prosthetic groups. The terms coenzyme and prosthetic group are frequently used synonymously. Naturally, it is often difficult to decide what is easily dissociable and what is not, for there is a complete range of possibilities.
P. Karlson, Charles H. Doering
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Publisher Summary This chapter provides an overview of coenzymes and prosthetic groups. The terms coenzyme and prosthetic group are frequently used synonymously. Naturally, it is often difficult to decide what is easily dissociable and what is not, for there is a complete range of possibilities.
P. Karlson, Charles H. Doering
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Requirement of acetyl-coenzyme A carboxylase kinase for coenzyme A
Archives of Biochemistry and Biophysics, 1983Phosphorylation and inactivation of acetyl-coenzyme A (CoA) carboxylase by acetyl-CoA carboxylase kinase in the presence of ATP and Mg2+ requires coenzyme A. Coenzyme A did not enhance the phosphorylation of alternative substrates of the carboxylase kinase such as protamine or histones.
Bruce A. Lent, Ki-Han Kim
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Synthesis of arachidonoyl coenzyme A and docosahexaenoyl coenzyme A in retina
Current Eye Research, 1984The synthesis of 14C-labeled arachidonoyl coenzyme A (CoA) and docosahexaenoyl CoA was studied in the human, bovine, rat and frog retina. The synthesis of arachidonoyl CoA was two- to fourfold higher than that of docosahexaenoyl CoA in the retinal membranes examined.
Nicolas G. Bazan, T. Sanjeeva Reddy
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[57] Coenzyme Q and analogs for coenzymic activity
1978Publisher Summary This chapter focuses on the coenzyme Q and the analogs for coenzymic activity. The form of coenzyme Q in human tissue is coenzyme Q 10 . Many mammalian species also contain coenzyme Q 10 (CoQ 10 ), but some rodents such as rats and mice may contain both coenzymes Q 9 and Q 10 (VII).
Yieh-Ping Wan, Karl Folkers
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Alternative coenzymes for biocatalysis
Current Opinion in Biotechnology, 2019Coenzymes are ubiquitous in Nature, assisting in enzyme-catalysed reactions. Several coenzymes, nicotinamides and flavins, have been known for close to a century, whereas variations of those organic molecules have more recently come to light. In general, the requirement of these coenzymes imposes certain constraints for in vitro enzyme use in ...
Guarneri, Alice +2 more
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Biosystems, 1980
The biosyntheses of the coenzymes exhibit various characteristics consistent with the idea that coenzymes evolved from very simple beginning through a succession of symbiotic unions.
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The biosyntheses of the coenzymes exhibit various characteristics consistent with the idea that coenzymes evolved from very simple beginning through a succession of symbiotic unions.
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Coenzyme A: to make it or uptake it?
Nature Reviews Molecular Cell Biology, 2016The consensus has been that intracellular coenzyme A (CoA) is obtained exclusively by de novo biosynthesis via a universal, conserved five-step pathway in the cell cytosol. However, old and new evidence suggest that cells (and some microorganisms) have several strategies to obtain CoA, with 4'-phosphopantetheine (P-PantSH; the fourth intermediate in ...
Ody C. M. Sibon, Erick Strauss
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Fetal Diagnosis and Therapy, 1996
Our objectives were to assess the plasma coenzyme Q10 (CoQ10) levels in normal pregnancy, in pregnancy with a spontaneous contractile event, in spontaneous abortion and in threatened abortion. Six hundred and fifteen CoQ10 levels were analyzed in 483 pregnant women: 350 patients were employed to design a normal curve; 66 patients with spontaneous ...
Noia, Giuseppe +6 more
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Our objectives were to assess the plasma coenzyme Q10 (CoQ10) levels in normal pregnancy, in pregnancy with a spontaneous contractile event, in spontaneous abortion and in threatened abortion. Six hundred and fifteen CoQ10 levels were analyzed in 483 pregnant women: 350 patients were employed to design a normal curve; 66 patients with spontaneous ...
Noia, Giuseppe +6 more
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