Results 241 to 250 of about 136,670 (296)

Coenzyme Q10 and rikkunshito prevent age-related changes in mouse otolith morphology and function. [PDF]

Biochem Biophys Rep
Ueda K, Imai T, Okayasu T, Tanaka T, Tatsumi K, Wanaka A, Kitahara T.   +6 more
europepmc   +1 more source

Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage

Aging Cell, EarlyView.
Chronic NAD depletion in fibroblasts lowers NAD levels, increases mitochondrial mass, and triggers an interferon‐dependent inflammatory response via mtDNA leakage through VDAC1, activating the cGAS‐STING pathway. This links NAD deficiency to metabolic and inflammatory processes, with implications for diseases associated with NAD decline.
Claudia C. S. Chini, Laura Colman, Eduardo Palmieri, Jessica L. Strange, Sonu Kashyap, Bing Han, Andres Benitez‐Rosendo, Gina L. Ciccio Lopez, Sara Peixoto Rabelo, Shreyartha Mukherjee, Gustavo H. de Souza, John Varga, Ralph G. Meyer, Mirella L. Meyer‐Ficca, Eduardo N. Chini   +14 more
wiley   +1 more source

Comprehensive diagnostic and therapeutic approach to male factor infertility aimed at natural fertility: A multicentric retrospective cohort study

Andrology, EarlyView.
Abstract Background In infertile couples whose male partner has alterations in semen parameters frequently, a comprehensive andrological approach is lacking and approximately 30–50% are classified as idiopathic infertility. These couples are often directly addressed to assisted reproduction techniques (ARTs).
Giuseppe Grande, Andrea Garolla, Andrea Graziani, Anna Laura Astorri, Maria Vittoria Cammarota, Annamaria Merola, Maria Pia Polidori, Emanuela Lulli, Enrico Busato, Francesco Pesce, Giuseppina Pompa, Alfredo Pontecorvi, Domenico Milardi, Alberto Ferlin   +13 more
wiley   +1 more source

Re-engineering of acetyl coenzyme A metabolism prevents senescence in budding yeast

Hadj-Moussa H, Ulusan M, Horkai D, Mirza MKA, Houseley J.   +4 more
europepmc   +1 more source

Energy metabolism disorders in migraine: triggers, pathways, and therapeutic repurposing. [PDF]

Front Neurol
Sun WX, Chen TY, Song MM, Gao YJ, Xu SY.
europepmc   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

High expression of stearoyl-coenzyme A desaturase in colorectal cancer oncogenic functions and its potential as a therapeutic target. [PDF]

World J Gastrointest Surg
Wang XW, Huang WY, Qin K, Zeng DT, Chen ZY, Chi BT, Tang YX, Li Q, Li B, Li DM, He RQ, Huang WJ, Chen G, Tang RX, Feng ZB.   +14 more
europepmc   +1 more source

Systematic Review Suggests Nutraceuticals Containing Vitamin B2 Could Provide an Alternative Treatment for Paediatric Migraines

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this review is to systematically summarise the evidence on the effectiveness of riboflavin (vitamin B2) or supplements containing riboflavin in preventing paediatric migraines. Methods This systematic review followed the Joanna Briggs Institute methodology and is reported to adhere to the Preferred Reporting Items for Systematic
Elisa Martello, Fatimah Aiyelabegan, Jemma Orr, Emma Wilson, Joanne R. Morling, Maria Kinali, Titus Joseph, Dirontsho Koboto, Surakshya Dhungana, Prudence Ikechukwu, Princella Seripenah, Heidi Emery, James Stewart‐Evans, Jo Leonardi‐Bee   +13 more
wiley   +1 more source

Evaluating the impact of coenzyme Q10 and high-intensity interval training on lactate threshold and Plasma blood gases in rats: a randomized controlled trial. [PDF]

Eur J Appl Physiol
Yasul Y, Yılmaz B, Şenel Ö, Kurt D, Akbulut T, Çalıkuşu A, Anadol E, Yılmaz C.   +7 more
europepmc   +1 more source