Results 241 to 250 of about 148,184 (310)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

Prebiotic aqueous reactions catalyzed by native nickel without hydrogen

open access: yesThe FEBS Journal, EarlyView.
Serpentinizing (H2‐producing) hydrothermal vents are candidate environments for metabolic origin. They generate highly reducing conditions that convert CO2 to formate and methane in abiotic reactions resembling reactions of the acetyl‐CoA pathway of CO2 fixation. They also contain natural catalysts. Native nickel (Ni0), like Fe0, Co0, and their alloys,
Carolina Garcia Garcia   +2 more
wiley   +1 more source

The effect of SIRT1 knockdown on the gene expression of CoQ10 biosynthetic enzymes. [PDF]

open access: yesJ Clin Biochem Nutr
Okuizumi R   +5 more
europepmc   +1 more source

Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD<sup>+</sup>-bound protomer chains. [PDF]

open access: yesActa Crystallogr F Struct Biol Commun
Zupko SP   +13 more
europepmc   +1 more source

Draft genome sequence data on <i>Methanosarcina mazei</i> OFF1024 isolated from paddy field of Pondicherry, India. [PDF]

open access: yesData Brief
Prathaban M   +6 more
europepmc   +1 more source

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