Results 151 to 160 of about 80,404 (288)

Advances in Understanding the Pathogenesis of Sensorineural Hearing Loss: Treatment Strategies and Implications for Auditory Protection

open access: yesSensory Neuroscience, Volume 1, Issue 1, April 2025.
Environmental factors and genetic factors damage the cochlear hair cells, which in turn leads to the death of sensory hair cells (This illustration was generated using Biorender.com). ABSTRACT Sensorineural hearing loss (SNHL) is a prevalent multifactorial condition affecting over 1.5 billion people worldwide.
Lin Yan   +12 more
wiley   +1 more source

European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management

open access: yesUnited European Gastroenterology Journal, Volume 13, Issue 3, Page 427-471, April 2025.
ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non‐gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well‐structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut‐brain interaction ...
Carolina Malagelada   +34 more
wiley   +1 more source

Extended longevity of termite kings and queens is accompanied by extranuclear localization of telomerase in somatic organs and caste‐specific expression of its isoforms

open access: yesInsect Science, Volume 32, Issue 2, Page 364-384, April 2025.
We recently reported that long‐lived termite kings and queens display an increased enzymatic activity and abundance of telomerase in their soma when compared to short‐lived workers. We hypothesized that this telomerase activation may represent its noncanonical pro‐longevity function, independent of its canonical role in telomere maintenance.
Marie Pangrácová   +6 more
wiley   +1 more source

Identifying ENO1 as a protein target of chlorogenic acid to inhibit cellular senescence and prevent skin photoaging in mice

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
A schematic depiction of chlorogenic acid inhibited UVA‐induced cellular senescence and mouse skin photoaging by suppressing the activity of Enolase 1 (ENO1) protein to block glycolytic pathway. Abstract Cellular senescence plays a critical role in repeated ultraviolet (UV) exposure‐induced skin photoaging. Currently, from the perspective of regulating
Xueling He   +11 more
wiley   +1 more source

Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats [PDF]

open access: green, 2004
Paulo J. Oliveira   +8 more
openalex   +1 more source

Acupuncture Versus Standard Medical Care in the Prophylactic Treatment of Migraine: A Systematic Review and Meta‐Analysis

open access: yesEuropean Journal of Neurology, Volume 32, Issue 4, April 2025.
ABSTRACT Background Although innovative pharmacological therapies for migraine prevention are now available, they may not be suitable or effective for all patients due to concerns about tolerability and the varying complexity of the underlying condition.
Francesca Pistoia   +7 more
wiley   +1 more source

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