Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero +8 more
wiley +1 more source
Precision gene diagnosis and treatment of epilepsy: a new frontier in medical care. [PDF]
Mu J, Jiang W, Tang Y, Zhou D, Liao W.
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Prebiotic aqueous reactions catalyzed by native nickel without hydrogen
Serpentinizing (H2‐producing) hydrothermal vents are candidate environments for metabolic origin. They generate highly reducing conditions that convert CO2 to formate and methane in abiotic reactions resembling reactions of the acetyl‐CoA pathway of CO2 fixation. They also contain natural catalysts. Native nickel (Ni0), like Fe0, Co0, and their alloys,
Carolina Garcia Garcia +2 more
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Optimizing nitrogen and sulfur supplementation for enhanced growth and biochemical composition in Solanum lycopersicum under hydroponic conditions. [PDF]
Anjum MA +11 more
europepmc +1 more source
Glutamate dehydrogenase from Pantoea ananatis: A new bacterial enzyme with dual coenzyme specificity. [PDF]
Kharchenko MS +3 more
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Label-free method to monitor metabolism during long-term culture of human pluripotent stem cell derived cardiomyocytes. [PDF]
Qian T +6 more
europepmc +1 more source
Exploring the role of riboflavin in swine well-being: a literature review. [PDF]
Shastak Y, Pelletier W.
europepmc +1 more source
Cost-effective whole-cell biosynthesis of ursodeoxycholic acid using engineered Escherichia coli with a multienzyme cascade. [PDF]
Zhang X +8 more
europepmc +1 more source

