Results 11 to 20 of about 188,158 (291)

Peroxisomal Cofactor Transport [PDF]

Biomolecules, 2020
Peroxisomes are eukaryotic organelles that are essential for growth and development. They are highly metabolically active and house many biochemical reactions, including lipid metabolism and synthesis of signaling molecules.
Anastasija Plett, Lennart Charton, Nicole Linka   +2 more
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Biochemical Characterization and Structural Insight into Interaction and Conformation Mechanisms of Serratia marcescens Lysine Decarboxylase (SmcadA)

Molecules, 2021
Inducible lysine decarboxylases (LDCs) are essential in various cellular processes of microorganisms and plants, especially under acid stress, which induces the expression of genes encoding LDCs.
Tolbert Osire, Zhina Qiao, Taowei Yang, Meijuan Xu, Xian Zhang, Zhiming Rao   +5 more
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Food Regime for Phenylketonuria: Presenting Complications and Possible Solutions

Journal of Multidisciplinary Healthcare, 2022
Sudipt Kumar Dalei, Nidhi Adlakha Regional Center for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, IndiaCorrespondence: Nidhi Adlakha Email nidhi.adlakha@rcb.res.inAbstract: In the category of rare inherited genetic disorders ...
Kumar Dalei S, Adlakha N
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Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells

Frontiers in Immunology, 2021
Cofactors may explain why in some cases food ingestion leads to anaphylaxis while in others elicits a milder reaction or tolerance. With cofactors, reactions become more severe and/or have a lower allergen threshold. Cofactors are present in up to 58% of
Rosa Muñoz-Cano, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Clara San Bartolome, Clara San Bartolome, Clara San Bartolome, Rocío Casas-Saucedo, Rocío Casas-Saucedo, Rocío Casas-Saucedo, Giovanna Araujo, Giovanna Araujo, Sonia Gelis, Sonia Gelis, Maria Ruano-Zaragoza, Maria Ruano-Zaragoza, Maria Ruano-Zaragoza, Jordi Roca-Ferrer, Jordi Roca-Ferrer, Jordi Roca-Ferrer, Francis Palomares, Francis Palomares, Margarita Martin, Margarita Martin, Margarita Martin, Joan Bartra, Joan Bartra, Joan Bartra, Joan Bartra, Mariona Pascal, Mariona Pascal, Mariona Pascal   +31 more
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Pterin function in bacteria

Pteridines, 2017
Pterins are widely conserved biomolecules that play essential roles in diverse organisms. First described as enzymatic cofactors in eukaryotic systems, bacterial pterins were discovered in cyanobacteria soon after.
Feirer Nathan, Fuqua Clay
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Non‐DNA‐binding cofactors enhance DNA‐binding specificity of a transcriptional regulatory complex

Molecular Systems Biology, 2011
Recruitment of cofactors to specific DNA sites is integral for specificity in gene regulation. As a model system, we examined how targeting and transcriptional control of the sulfur metabolism genes in Saccharomyces cerevisiae is governed by recruitment ...
Trevor Siggers, Michael H Duyzend, Jessica Reddy, Sidra Khan, Martha L Bulyk   +4 more
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Characterizing metabolic drivers of Clostridioides difficile infection with activity-based hydrazine probes

Frontiers in Pharmacology, 2023
Many enzymes require post-translational modifications or cofactor machinery for primary function. As these catalytically essential moieties are highly regulated, they act as dual sensors and chemical handles for context-dependent metabolic activity ...
Katelyn A. Bustin, Arwa Abbas, Xie Wang, Michael C. Abt, Joseph P. Zackular, Joseph P. Zackular, Megan L. Matthews   +6 more
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Identification and Expression Analysis of an Atypical Alkaline Phosphatase in Emiliania huxleyi

Frontiers in Microbiology, 2018
Emiliania huxleyi, a cosmopolitan coccolithophore in the modern ocean, plays an important role in the carbon cycle and local climate feedback as it can form extensive blooms, calcify, and produce dimethylsulfoniopropionate (DMSP) leading to the ...
Tangcheng Li, Chentao Guo, Yaqun Zhang, Cong Wang, Xin Lin, Senjie Lin, Senjie Lin   +6 more
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CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants

Cell Genomics, 2022
Summary: Non-coding DNA variants (NCVs) impact gene expression by altering binding sites for regulatory complexes. New high-throughput methods are needed to characterize the impact of NCVs on regulatory complexes.
David Bray, Heather Hook, Rose Zhao, Jessica L. Keenan, Ashley Penvose, Yemi Osayame, Nima Mohaghegh, Xiaoting Chen, Sreeja Parameswaran, Leah C. Kottyan, Matthew T. Weirauch, Trevor Siggers   +11 more
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Genome-Scale Mining of Acetogens of the Genus Clostridium Unveils Distinctive Traits in [FeFe]- and [NiFe]-Hydrogenase Content and Maturation

Microbiology Spectrum, 2022
Knowledge of the organizational and functional properties of hydrogen metabolism is pivotal to the construction of a framework supportive of a hydrogen-fueled low-carbon economy. Hydrogen metabolism relies on the mechanism of action of hydrogenases.
Pier Francesco Di Leonardo, Giacomo Antonicelli, Valeria Agostino, Angela Re   +3 more
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