Identification of YdhV as the first molybdoenzyme binding a Bis-Mo-MPT cofactor in escherichia coli [PDF]
, 2019 The oxidoreductase YdhV in Escherichia coli has been predicted to belong to the family of molybdenum/tungsten cofactor (Moco/Wco)-containing enzymes. In this study, we characterized the YdhV protein in detail, which shares amino acid sequence homology ...
Dau, Holger +7 more
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The Geometry of the Catalytic Active Site in [FeFe]-hydrogenases is Determined by Hydrogen Bonding and Proton Transfer [PDF]
, 2019 [FeFe]-hydrogenases are efficient metalloenzymes that catalyze the oxidation and evolution of molecular hydrogen, H2. They serve as a blueprint for the design of synthetic H2-forming catalysts.
Apfel, Ulf-Peter +11 more
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Journal of Biological Chemistry, 2013 The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase.
openaire +2 more sources
The role of algebraic solutions in planar polynomial differential systems [PDF]
, 2005 We study a planar polynomial differential system, given by \dot{x}=P(x,y), \dot{y}=Q(x,y). We consider a function I(x,y)=\exp \{h_2(x) A_1(x,y) \diagup A_0(x,y) \} h_1(x) \prod_{i=1}^{\ell} (y-g_i(x))^{\alpha_i}, where g_i(x) are algebraic functions, A_1(
Giacomini, Héctor +2 more
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Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB. [PDF]
, 2020 NifB is a radical S-adenosyl-L-methionine (SAM) enzyme that is essential for nitrogenase cofactor assembly. Previously, a nitrogen ligand was shown to be involved in coupling a pair of [Fe4S4] clusters (designated K1 and K2) concomitant with carbide ...
Britt, R David +7 more
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Integrability of planar polynomial differential systems through linear differential equations [PDF]
, 2005 In this work, we consider rational ordinary differential equations dy/dx = Q(x,y)/P(x,y), with Q(x,y) and P(x,y) coprime polynomials with real coefficients.
Giacomini, Héctor +2 more
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Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone [PDF]
, 2000 We have applied the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens to a cell-free system for the regeneration of the nicotinamide cofactors NAD and NADP in the biological production of the important semisynthetic opiate drug ...
Boonstra, B +4 more
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Conformational Transitions Accompanying Oligomerization of Yeast Alcohol Oxidase, a Peroxisomal Flavoenzyme [PDF]
, 1999 Alcohol oxidase (AO) is a homo-octameric flavoenzyme which catalyzes methanol oxidation in methylotrophic yeasts. AO protein is synthesized in the cytosol and subsequently sorted to peroxisomes where the active enzyme is formed.
Boteva, R +6 more
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Cofactor and Cofactor Mimetics
Blood, 2019 Many natural enzymes need the assistance of protein cofactors to catalyze chemical reactions at a physiologically relevant speed and several of the enzymes that make up for the coagulation cascade are no exception in this regard. Notably, activated factors VII, IX and X display relatively poor enzymatic activity towards their respective macromolecular ...
openaire +1 more source
Texture and Cofactor Zeros of the Neutrino Mass Matrix
, 2014 We study Majorana neutrino mass matrices that have two texture zeros, or two cofactor zeros, or one texture zero and one cofactor zero. The two texture/cofactor zero conditions give four constraints, which in conjunction with the five measured ...
Liao, Jiajun, Marfatia, D., Whisnant, K.
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