Results 21 to 30 of about 221,534 (298)

Mechanisms, Cofactors, and Augmenting Factors Involved in Anaphylaxis

Frontiers in Immunology, 2017
Anaphylaxis is an acute and life-threatening systemic reaction. Many triggers have been described, including food, drug, and hymenoptera allergens, which are the most frequently involved. The mechanisms described in anaphylactic reactions are complex and
Rosa Muñoz-Cano, Rosa Muñoz-Cano, Mariona Pascal, Mariona Pascal, Giovanna Araujo, Giovanna Araujo, M. J. Goikoetxea, Antonio L. Valero, Antonio L. Valero, Cesar Picado, Cesar Picado, Joan Bartra, Joan Bartra   +12 more
doaj   +1 more source

Cofactors of drug hypersensitivity—A monocenter retrospective analysis

Frontiers in Allergy, 2023
BackgroundDrug hypersensitivity reactions (DHRs) are major medical problems that influence the treatment of patients by both under- and overdiagnosis.
Johanna Kühl, Björn Bergh, Matthias Laudes, Silke Szymczak, Guido Heine   +4 more
doaj   +1 more source

‐cofactor

, 2022
Azotobacter vinelandii produces three genetically distinct, but structurally and mechanistically similar nitrogenase isozymes designated as Mo‐dependent, V‐dependent, or Fe‐only based on the heterometal contained within their associated active site ...
Ana Pérez‐González, Lance C. Seefeldt, Dennis R. Dean, Pérez-González, Ana, Jimenez‐Vicente, Emilio, Emilio Jimenez‐Vicente, Derek F. Harris, Dean, Dennis R., Alvaro Salinero‐Lanzarote, Salinero-Lanzarote, Alvaro, Harris, Derek F., Pérez‐González, Ana, Jiménez-Vicente, Emilio, Salinero‐Lanzarote, Alvaro, Harris, Derek F, Seefeldt, Lance C.   +15 more
core   +1 more source

A 7-Deazaadenosylaziridine Cofactor for Sequence-Specific Labeling of DNA by the DNA Cytosine-C5 Methyltransferase M.HhaI

Molecules, 2015
DNA methyltransferases (MTases) catalyze the transfer of the activated methyl group of the cofactor S-adenosyl-l-methionine (AdoMet or SAM) to the exocyclic amino groups of adenine or cytosine or the C5 ring atom of cytosine within specific DNA sequences.
Falk Kunkel, Rudi Lurz, Elmar Weinhold
doaj   +1 more source

Biochemical Characterization and Structural Insight into Interaction and Conformation Mechanisms of Serratia marcescens Lysine Decarboxylase (SmcadA)

Molecules, 2021
Inducible lysine decarboxylases (LDCs) are essential in various cellular processes of microorganisms and plants, especially under acid stress, which induces the expression of genes encoding LDCs.
Tolbert Osire, Zhina Qiao, Taowei Yang, Meijuan Xu, Xian Zhang, Zhiming Rao   +5 more
doaj   +1 more source

The Molybdenum Cofactor [PDF]

Journal of Biological Chemistry, 2013
The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase.
openaire   +2 more sources

Pteridines CVII* Synthesis of 6-Azidomethyl-5,6,7,8-tetrahydropterin. Photo degradation Products and Cofactor Properties on Aromatic Amino Acid Monooxygenases

Pteridines, 1995
The synthesis of 6-azidomethyl-5,6,7,8-tetrahydropterin (6-AzmH4Ptr) (9) starting from 2,4-diamino- 6-hydroxymethylpteridine (1) is described. A special protecting group strategy had to be applied to perform the structural modifications. The introduction
Heizmann Gerhard, Groehn Viola, Almås Bjørg, Haavik Jan, Flatmark Torgeir, Pfleiderer Wolfgang   +5 more
doaj   +1 more source

Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells

Frontiers in Immunology, 2021
Cofactors may explain why in some cases food ingestion leads to anaphylaxis while in others elicits a milder reaction or tolerance. With cofactors, reactions become more severe and/or have a lower allergen threshold. Cofactors are present in up to 58% of
Rosa Muñoz-Cano, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Clara San Bartolome, Clara San Bartolome, Clara San Bartolome, Rocío Casas-Saucedo, Rocío Casas-Saucedo, Rocío Casas-Saucedo, Giovanna Araujo, Giovanna Araujo, Sonia Gelis, Sonia Gelis, Maria Ruano-Zaragoza, Maria Ruano-Zaragoza, Maria Ruano-Zaragoza, Jordi Roca-Ferrer, Jordi Roca-Ferrer, Jordi Roca-Ferrer, Francis Palomares, Francis Palomares, Margarita Martin, Margarita Martin, Margarita Martin, Joan Bartra, Joan Bartra, Joan Bartra, Joan Bartra, Mariona Pascal, Mariona Pascal, Mariona Pascal   +31 more
doaj   +1 more source

Membrane electrochemical reactors (MER) for NADH regeneration in HLADH-catalysed synthesis: comparison of effectiveness [PDF]

, 2004
Two membrane electrochemical reactors(MER) were designed and applied to HLADH-catalysed reduction of cyclohexanone to cyclohexanol. The regeneration of the cofactor NADH was ensured electrochemically, using either methyl viologen or a rhodium complex as
Basséguy, Régine, Bergel, Alain, Délécouls-Servat, Karine   +2 more
core   +1 more source

Theoretical Studies of Biological Nitrogen Fixation. I. Density Functional Modeling of the Mo-Site of the FeMo-Cofactor

, 2016
The Mo-site and its ligand environment of the FeMo-cofactor (FeMo-co) were studied using the hybrid density functional method B3LYP. The structure and stability of the model complex (S-ligand)3(N-ligand)Mo[(S)-OCH(CH3)C(O)O−] along with its various ...
Djamaladdin G. Musaev (1391992), Robert K. Szilagyi (1590487), Keiji Morokuma (1247166)   +2 more
core   +2 more sources