Results 21 to 30 of about 184,152 (265)

Biochemical Characterization and Structural Insight into Interaction and Conformation Mechanisms of Serratia marcescens Lysine Decarboxylase (SmcadA)

Molecules, 2021
Inducible lysine decarboxylases (LDCs) are essential in various cellular processes of microorganisms and plants, especially under acid stress, which induces the expression of genes encoding LDCs.
Tolbert Osire, Zhina Qiao, Taowei Yang, Meijuan Xu, Xian Zhang, Zhiming Rao   +5 more
doaj   +1 more source

The CoFactor database: organic cofactors in enzyme catalysis [PDF]

Bioinformatics, 2010
Abstract Motivation: Organic enzyme cofactors are involved in many enzyme reactions. Therefore, the analysis of cofactors is crucial to gain a better understanding of enzyme catalysis. To aid this, we have created the CoFactor database. Results: CoFactor provides a web interface to access hand-curated data extracted from ...
Julia D. Fischer, Gemma L. Holliday, Janet M. Thornton   +2 more
openaire   +2 more sources

Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells

Frontiers in Immunology, 2021
Cofactors may explain why in some cases food ingestion leads to anaphylaxis while in others elicits a milder reaction or tolerance. With cofactors, reactions become more severe and/or have a lower allergen threshold. Cofactors are present in up to 58% of
Rosa Muñoz-Cano, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Clara San Bartolome, Clara San Bartolome, Clara San Bartolome, Rocío Casas-Saucedo, Rocío Casas-Saucedo, Rocío Casas-Saucedo, Giovanna Araujo, Giovanna Araujo, Sonia Gelis, Sonia Gelis, Maria Ruano-Zaragoza, Maria Ruano-Zaragoza, Maria Ruano-Zaragoza, Jordi Roca-Ferrer, Jordi Roca-Ferrer, Jordi Roca-Ferrer, Francis Palomares, Francis Palomares, Margarita Martin, Margarita Martin, Margarita Martin, Joan Bartra, Joan Bartra, Joan Bartra, Joan Bartra, Mariona Pascal, Mariona Pascal, Mariona Pascal   +31 more
doaj   +1 more source

Identification and Expression Analysis of an Atypical Alkaline Phosphatase in Emiliania huxleyi

Frontiers in Microbiology, 2018
Emiliania huxleyi, a cosmopolitan coccolithophore in the modern ocean, plays an important role in the carbon cycle and local climate feedback as it can form extensive blooms, calcify, and produce dimethylsulfoniopropionate (DMSP) leading to the ...
Tangcheng Li, Chentao Guo, Yaqun Zhang, Cong Wang, Xin Lin, Senjie Lin, Senjie Lin   +6 more
doaj   +1 more source

Biological Catalysis and Information Storage Have Relied on N-Glycosyl Derivatives of β-D-Ribofuranose since the Origins of Life

Biomolecules, 2023
Most naturally occurring nucleotides and nucleosides are N-glycosyl derivatives of β-d-ribose. These N-ribosides are involved in most metabolic processes that occur in cells.
Katarzyna Wozniak, Krzysztof Brzezinski
doaj   +1 more source

Mechanisms, Cofactors, and Augmenting Factors Involved in Anaphylaxis

Frontiers in Immunology, 2017
Anaphylaxis is an acute and life-threatening systemic reaction. Many triggers have been described, including food, drug, and hymenoptera allergens, which are the most frequently involved. The mechanisms described in anaphylactic reactions are complex and
Rosa Muñoz-Cano, Rosa Muñoz-Cano, Mariona Pascal, Mariona Pascal, Giovanna Araujo, Giovanna Araujo, M. J. Goikoetxea, Antonio L. Valero, Antonio L. Valero, Cesar Picado, Cesar Picado, Joan Bartra, Joan Bartra   +12 more
doaj   +1 more source

A 7-Deazaadenosylaziridine Cofactor for Sequence-Specific Labeling of DNA by the DNA Cytosine-C5 Methyltransferase M.HhaI

Molecules, 2015
DNA methyltransferases (MTases) catalyze the transfer of the activated methyl group of the cofactor S-adenosyl-l-methionine (AdoMet or SAM) to the exocyclic amino groups of adenine or cytosine or the C5 ring atom of cytosine within specific DNA sequences.
Falk Kunkel, Rudi Lurz, Elmar Weinhold
doaj   +1 more source

Pteridines CVII* Synthesis of 6-Azidomethyl-5,6,7,8-tetrahydropterin. Photo degradation Products and Cofactor Properties on Aromatic Amino Acid Monooxygenases

Pteridines, 1995
The synthesis of 6-azidomethyl-5,6,7,8-tetrahydropterin (6-AzmH4Ptr) (9) starting from 2,4-diamino- 6-hydroxymethylpteridine (1) is described. A special protecting group strategy had to be applied to perform the structural modifications. The introduction
Heizmann Gerhard, Groehn Viola, Almås Bjørg, Haavik Jan, Flatmark Torgeir, Pfleiderer Wolfgang   +5 more
doaj   +1 more source

The Molybdenum Cofactor [PDF]

Journal of Biological Chemistry, 2013
The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase.
openaire   +2 more sources

Characterization of an M-Cluster-Substituted Nitrogenase VFe Protein

mBio, 2018
The Mo- and V-nitrogenases are two homologous members of the nitrogenase family that are distinguished mainly by the presence of different heterometals (Mo or V) at their respective cofactor sites (M- or V-cluster).
Johannes G. Rebelein, Chi Chung Lee, Megan Newcomb, Yilin Hu, Markus W. Ribbe   +4 more
doaj   +1 more source