Results 31 to 40 of about 341,197 (295)

Non‐DNA‐binding cofactors enhance DNA‐binding specificity of a transcriptional regulatory complex

open access: yesMolecular Systems Biology, 2011
Recruitment of cofactors to specific DNA sites is integral for specificity in gene regulation. As a model system, we examined how targeting and transcriptional control of the sulfur metabolism genes in Saccharomyces cerevisiae is governed by recruitment ...
Trevor Siggers   +4 more
doaj   +1 more source

CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants

open access: yesCell Genomics, 2022
Summary: Non-coding DNA variants (NCVs) impact gene expression by altering binding sites for regulatory complexes. New high-throughput methods are needed to characterize the impact of NCVs on regulatory complexes.
David Bray   +11 more
doaj   +1 more source

Food Regime for Phenylketonuria: Presenting Complications and Possible Solutions

open access: yesJournal of Multidisciplinary Healthcare, 2022
Sudipt Kumar Dalei, Nidhi Adlakha Regional Center for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, IndiaCorrespondence: Nidhi Adlakha Email nidhi.adlakha@rcb.res.inAbstract: In the category of rare inherited genetic disorders ...
Kumar Dalei S, Adlakha N
doaj  

One diagonal texture or cofactor zero of the neutrino mass matrix

open access: yes, 2013
In view of the recent measurement of nonzero $\theta_{13}$, we carry out a systematic study of a simple class of neutrino models that has one diagonal texture or cofactor zero in the mass matrix.
Liao, Jiajun   +2 more
core   +1 more source

Pterin function in bacteria

open access: yesPteridines, 2017
Pterins are widely conserved biomolecules that play essential roles in diverse organisms. First described as enzymatic cofactors in eukaryotic systems, bacterial pterins were discovered in cyanobacteria soon after.
Feirer Nathan, Fuqua Clay
doaj   +1 more source

Genome-Scale Mining of Acetogens of the Genus Clostridium Unveils Distinctive Traits in [FeFe]- and [NiFe]-Hydrogenase Content and Maturation

open access: yesMicrobiology Spectrum, 2022
Knowledge of the organizational and functional properties of hydrogen metabolism is pivotal to the construction of a framework supportive of a hydrogen-fueled low-carbon economy. Hydrogen metabolism relies on the mechanism of action of hydrogenases.
Pier Francesco Di Leonardo   +3 more
doaj   +1 more source

Texture and Cofactor Zeros of the Neutrino Mass Matrix

open access: yes, 2014
We study Majorana neutrino mass matrices that have two texture zeros, or two cofactor zeros, or one texture zero and one cofactor zero. The two texture/cofactor zero conditions give four constraints, which in conjunction with the five measured ...
Liao, Jiajun, Marfatia, D., Whisnant, K.
core   +1 more source

How many metals does it take to fix N2? A mechanistic overview of biological nitrogen fixation [PDF]

open access: yes, 2006
During the process of biological nitrogen fixation, the enzyme nitrogenase catalyzes the ATP-dependent reduction of dinitrogen to ammonia. Nitrogenase consists of two component metalloproteins, the iron (Fe) protein and the molybdenum-iron (MoFe) protein;
Howard, James B., Rees, Douglas C.
core   +1 more source

Classical planar algebraic curves realizable by quadratic polynomial differential systems [PDF]

open access: yes, 2017
In this paper we show planar quadratic polynomial differentialsystems exhibiting as solutions some famous planar invariant algebraic curves. Also we put particular attention to the Darboux integrability of these differential systems.The author is ...
García, I. A. (Isaac A.), Llibre, Jaume
core   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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