Results 191 to 200 of about 419,459 (324)

Dual Disruption of the Immune Cytokine Spätzle Facilitates Fungal Infection of Diverse Insect Hosts

Advanced Science, EarlyView.
The Toll pathway is essential for insect defense against fungal pathogens. This works reports that fungal parasites employ two divergent virulent effectors to target the Toll receptor ligand Spätzle: a metalloprotease degrading it and a hairpin‐like effector hijacking it to block signal transduction. This dual strategy enables the fungus to kill a wide
Shuangxiu Song, Shiqin Li, Yujuan Luo, Dongxiang Wei, Junmei Shang, Hongyun Wu, Gangqi Fang, Chengshu Wang   +7 more
wiley   +1 more source

Reduction of NAD and NMN on mineral surfaces with H₂ reveals a functional role for the AMP moiety in a prebiotic context. [PDF]

Commun Chem
Henriques Pereira DP, Xie X, Stewart SV, Subrati Z, Beyazay T, Paczia N, Belz J, Volz K, Erastova V, Tüysüz H, Preiner M.   +10 more
europepmc   +1 more source

Defined Electrosynthetic Microbial Consortia Reveal Electron Transfer Modes Governing Acetate Production

Advanced Science, EarlyView.
Spatially resolved Shewanella–acetogen interactions link DIET and MET pathways to acetate formation, offering a generalizable framework for designing structured, high‐efficiency microbial electrosynthesis systems. Abstract Precise manipulation of interspecies electron transfer (IET) is critical for advancing microbial electrosynthesis (MES) toward ...
Jing Zhang, He Liu, Qihao Cao, Chao Zhang, Min Zhang, Minhua Cui, Yan Zhang, Bo Fu, Hongbo Liu   +8 more
wiley   +1 more source

Calculation of specificity constants Γ for RUBISCO of different species from microcalorimetric data. [PDF]

Photosynth Res
Frank J, Müh F.
europepmc   +1 more source

Novel cofactors via post-translational modifications of enzyme active sites [PDF]

, 2000
Nicole M. Okeley, Wilfred A. van der Donk   +1 more
openalex   +1 more source

DNA Origami and Its Applications in Synthetic Biology

Advanced Science, EarlyView.
This review provides a comprehensive summary of recent advancements in DNA origami for synthetic biology, emphasizing two key areas: the precise construction and dynamic regulation of extracellular‐to‐intracellular, and the synergistic integration with cell‐free systems.
Yaning Fang, Xuexin Chen, Qingsheng Qi, Min Lin, Quanfeng Liang   +4 more
wiley   +1 more source

A structure-oriented kinetics dataset of enzyme-substrate interactions. [PDF]

Sci Data
Krishnan SR, Pandey N, Srinivasan R, Roy A.   +3 more
europepmc   +1 more source

Removal of B-domain Sequences from Factor V Rather than Specific Proteolysis Underlies the Mechanism by Which Cofactor Function Is Realized [PDF]

, 2004
Raffaella Toso, Rodney M. Camire
openalex   +1 more source

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Regeneration of cofactor NAD(P)⁺ with NAD(P)H oxidase for the production of value-added chemicals. [PDF]

Front Bioeng Biotechnol
Zhou LJ, Long SX, Huan T, Wu Y, Zhang YW.   +4 more
europepmc   +1 more source