Results 211 to 220 of about 188,158 (291)

A structure-oriented kinetics dataset of enzyme-substrate interactions. [PDF]

Sci Data
Krishnan SR, Pandey N, Srinivasan R, Roy A.   +3 more
europepmc   +1 more source

Computer-aided design of stability enhanced nicotinamide cofactor biomimetics for cell-free biocatalysis

Alexandra P. Platt, Heidi Klem, S.J.B. Mallinson, Yannick J. Bomble, Robert S. Paton   +4 more
openalex   +1 more source

ATP‐Independent Turnover of Dinitrogen Intermediates Captured on the Nitrogenase Cofactor [PDF]

Chi Chung Lee, Martin Stang, Markus W. Ribbe, Yilin Hu   +3 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Calculation of specificity constants Γ for RUBISCO of different species from microcalorimetric data. [PDF]

Photosynth Res
Frank J, Müh F.
europepmc   +1 more source

Trans-Dominant Inhibition of Prion Propagation In Vitro Is Not Mediated by an Accessory Cofactor

, 2009
James C. Geoghegan, Michael B. Miller, Aimee H. Kwak, Brent T. Harris, Surachai Supattapone   +4 more
openalex   +2 more sources

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Regeneration of cofactor NAD(P)⁺ with NAD(P)H oxidase for the production of value-added chemicals. [PDF]

Front Bioeng Biotechnol
Zhou LJ, Long SX, Huan T, Wu Y, Zhang YW.   +4 more
europepmc   +1 more source

Revisiting the tubulin cofactors and Arl2 in the regulation of soluble αβ-tubulin pools and their effect on microtubule dynamics

, 2017
Jawdat Al‐Bassam
openalex   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source