Results 211 to 220 of about 418,378 (371)

Hooked for Decay with Hydrophobic-Coated Magnetic Beads to Grapple and Disintegrate Nanoplastics. [PDF]

Angew Chem Int Ed Engl
Wang D, Mao M, Lorberg M, Luka J, Bienstein M, Okuda J, Schwaneberg U.   +6 more
europepmc   +1 more source

SP3 and DEP1 Orchestrate Panicle Architecture by Jointly Regulating APO2 Expression in Rice

Advanced Science, EarlyView.
The transcription factor SP3 enhances inflorescence meristem activity and interacts with the cysteine‐rich domain of DEP1. This interaction alters DEP1's subcellular localization between the plasma membrane and nucleus, and suppresses SP3‐mediated transcriptional activation of APO2.
Yuexin Liu, Niannian Chen, Xiaowei Fan, Xueqing Xia, Yilong Yao, Wen Huang, Jin Sun, Lintao Huang, Lei Wang, Hong Yu, Jiayang Li, Yongzhong Xing   +11 more
wiley   +1 more source

A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen. [PDF]

Biochemistry
Peduzzi OM, Palowitch GM, Gajewski JP, Hu K, Wheeler A, Laremore TN, Silletti S, Komives EA, Allen BD, Silakov A, Krebs C, Bollinger JM, Lin CY, Boal AK.   +13 more
europepmc   +1 more source

Cofactor Requirements for the Formation of Δ9-Unsaturated Fatty Acids in Mycobacterium phlei

, 1964
Armand J. Fulco, Konrad E. Bloch
openalex   +1 more source

SCORCH2: A Generalized Heterogeneous Consensus Model for High‐Enrichment Interaction‐Based Virtual Screening

Advanced Science, EarlyView.
Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen, Vincent Blay, Pedro J. Ballester, Douglas R. Houston   +3 more
wiley   +1 more source

Cofactors and Erythrocyte Glycolytic Capacity

, 1966
K.K. Tsuboi, J.F. Allan, Keiko Fukunaga
openalex   +1 more source

Real‐Time Detection of Reduced Nitroreductase with a Reversible Fluorescent Probe

Advanced Science, EarlyView.
The first reversible binding probe (rNTRp) is presented that selectively detects the nitroreductase enzyme's active, reduced form (red‐NTR) with a fluorescence turn‐on response. Contrary to the conventional reaction‐based probes known to date, which provide only static information on the accumulated enzyme activity at a given time, rNTRp allows ...
Sourav Sarkar, Anushree Shil, Yong Woong Jun, Yun Jae Yang, Ranran Cheng, Wenli Wu, Xuechen Li, Qiongzheng Hu, Kyo Han Ahn   +8 more
wiley   +1 more source

Stereochemistry and Charged State Influence Effector Outcomes of d-2-Hydroxyglutarate Dehydrogenase Ligands. [PDF]

Biochemistry
Quaye JA, Gadda G.
europepmc   +1 more source

Fluorine-19 chemical shifts as structural probes of metal-sulfur clusters and the cofactor of nitrogenase. [PDF]

, 1982
P.K. Mascharak, Matt C. Smith, William H. Armstrong, Barbara K. Burgess, R. H. Holm   +4 more
openalex   +1 more source

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

Advanced Science, EarlyView.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan, Yinuo Liu, Lu‐ping Chi, Chaofan Yang, Shengying Li, Wei Zhang   +5 more
wiley   +1 more source