Results 241 to 250 of about 188,158 (291)

Transforming RNA Degradation into Accurate RNA Detection: RNase I–Assisted Rolling Circle Amplification for Clinical Samples

Angewandte Chemie, EarlyView.
Here, we transform this otherwise destructive enzymatic activity into a powerful diagnostic advantage through an RNase I–assisted rolling circle amplification (RI‐RCA) strategy. By integrating controlled RNase I–mediated RNA digestion with circular DNA templates, this approach enables direct and highly sensitive detection of target RNA sequences. Using
Amal Mathai, Cheng‐Yu Lee, Zijie Zhang, Jimmy Gu, John D. Brennan, Yingfu Li   +5 more
wiley   +1 more source

Hooked for Decay with Hydrophobic-Coated Magnetic Beads to Grapple and Disintegrate Nanoplastics. [PDF]

Angew Chem Int Ed Engl
Wang D, Mao M, Lorberg M, Luka J, Bienstein M, Okuda J, Schwaneberg U.   +6 more
europepmc   +1 more source

PCA‐Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation

Angewandte Chemie, EarlyView.
Database mining using principal component analysis (PCA)‐based clustering enabled discovery of bacterial enzymes capable of catalyzing stereodivergent cyclopropanation of styrene. Statistical analyses of sequence data further revealed characteristic structural properties of these enzymes, highlighting the potential of the bioinformatics tools for ...
Shunsuke Kato, Koki Takeuchi, Kohei Umeda, Hisashi Kudo, Tomohisa Hasunuma, Takashi Hayashi   +5 more
wiley   +1 more source

Comparative genomic analysis of hydrogen peroxide and nitric oxide metabolic pathways in Limosilactobacillus fermentum. [PDF]

Sci Rep
Eom JH, Cho MY, Choi EM, Kim JW, Yang SJ, Hwang J, Hwang I, Lee D, Kim YY, Kim HS, Baek H, Kim SJ.   +11 more
europepmc   +1 more source

Review: Changing paradigms for the micronutrient zinc, a known protein cofactor, as a signal relaying also cellular redox state — R0/PR3

Ute Krämer
openalex   +1 more source

Activity-Enhancing Mutations in an LmrR-Based Artificial Metalloenzyme Destabilize the Protein Scaffold and Alter its Conformational Plasticity. [PDF]

Chembiochem
Safeer AA, Casilli F, Beugelink W, Roelfes G, Baldus M, van Ingen H.   +5 more
europepmc   +1 more source

Allosteric Mechanisms Triggering Substrate and Cofactor Binding in the SULT1A1 Dimer as Revealed by Molecular Dynamics Simulations. [PDF]

J Chem Inf Model
Toth D, Dudas B, Nicot AB, Miteva MA, Balog E.   +4 more
europepmc   +1 more source

A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen. [PDF]

Biochemistry
Peduzzi OM, Palowitch GM, Gajewski JP, Hu K, Wheeler A, Laremore TN, Silletti S, Komives EA, Allen BD, Silakov A, Krebs C, Bollinger JM, Lin CY, Boal AK.   +13 more
europepmc   +1 more source

Malic enzyme-based system for transhydrogenation between nicotinamide cofactors. [PDF]

Synth Syst Biotechnol
Xue H, Hu Y, Shah AM, Wang X, Guo X, Huang Y, Zhao ZK.   +6 more
europepmc   +1 more source

Real-life safety of peanut oral immunotherapy: Results from a French multicenter observational study. [PDF]

J Allergy Clin Immunol Glob
Michaud E, Amat F, Lambert C, Divaret-Chauveau A, Deschildre A, Peanut Oral Immunotherapy Working Party from the French Society of Allergology.   +5 more
europepmc   +1 more source