Results 241 to 250 of about 413,042 (378)
Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies
Objective Aggregation of misfolded α‐synuclein (aSyn) within the brain is the pathologic hallmark of Lewy body diseases (LBDs), including Parkinson's disease (PD), and dementia with Lewy bodies (DLB) disease. Although evidence exists for aSyn “strains,” conformations with distinct biological properties, biomarkers for PD versus DLB are lacking.
George T. Kannarkat+17 more
wiley +1 more source
H3CP contributes to sustainable synthesis by integrating regioselective enzymatic halogenation, Pd‐catalyzed Heck coupling, and enzymatic hydrolysis. TPGS‐705‐M micelles enable the Pd‐catalyzed step, allowing seamless compatibility with enzymatic reactions in one vessel under aqueous conditions.
Ran Zhu+3 more
wiley +2 more sources
Electrocatalytic NAD(P)H regeneration for biosynthesis
The highly efficient chemoselectivity, stereoselectivity, and regioselectivity render enzyme catalysis an ideal pathway for the synthesis of various chemicals in broad applications.
Yaoxuan Li+8 more
doaj
Obligately Tungsten-Dependent Enzymes─Catalytic Mechanisms, Models and Applications. [PDF]
Szaleniec M, Heider J.
europepmc +1 more source
Evidence for methoxatin (pyrroloquinolinequinone) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy. [PDF]
Richard S. Moog+3 more
openalex +1 more source
Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor
M. Galli+8 more
semanticscholar +1 more source
Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere+4 more
wiley +1 more source
Malleicyprol, a virulence factor of notorious animal and human pathogens of the Burkholderia pseudomallei (BP) group, results from the fusion of two individual polyketide chains. The noncanonical condensation domain of the PKS–NRPS hybrid synthetase BurF forms an ester bond, and the terminal reductase domain mediates a reductive chain release followed ...
Jonas Fiedler+5 more
wiley +2 more sources
Defining the mechanism of action of the nitrofuranyl piperazine HC2210 against Mycobacterium abscessus. [PDF]
Eke IE+6 more
europepmc +1 more source