Results 241 to 250 of about 230,804 (297)

Beyond Single Enzymes: System-Level Fungal Transformation of Halogenated Nitrophenols. [PDF]

open access: yesJ Fungi (Basel)
Aguilar G   +8 more
europepmc   +1 more source

Cofactor squelching: Artifact or fact?

open access: yesBioEssays, 2016
Cofactor squelching is the term used to describe competition between transcription factors (TFs) for a limited amount of cofactors in a cell with the functional consequence that TFs in a given cell interfere with the activity of each other. Since cofactor squelching was proposed based primarily on reporter assays some 30 years ago, it has remained ...
Susanne Mandrup   +2 more
exaly   +5 more sources

Hierarchies of cofactor systems

open access: yesJournal of Physics A: Mathematical and General, 2002
Summary: We assign to any cofactor system a whole hierarchy of such systems. A sufficient condition for their complete integrability is given. The hierarchies admit construction of nontrivial integrable systems from trivial ones.
Topalov, P
openaire   +4 more sources
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Novel cofactor derivatives and cofactor-based models

Current Opinion in Chemical Biology, 1998
In 1997 and the first half of 1998, numerous publications appeared reporting studies of cofactors and their analogues in classical model systems and in enzyme-catalyzed reactions directed at understanding the enzymatic reactions of their natural cofactors. Model systems based on flavins have provided new insights into enzymatic modulation of the flavin
P K, Mishra, D G, Drueckhammer
openaire   +2 more sources

Cofactor dependent and cofactor independent anticardiolipin antibodies

Thrombosis Research, 1991
Two distinct types of anticardiolipin antibodies are described, one of which requires the presence of a serum factor (cofactor) to bind cardiolipin in ELISA and liposome affinity systems. The second type does not require this cofactor. The requirement of a cofactor for the binding of some but not all anticardiolipin antibodies provides an explanation ...
L W, Chamley, E J, McKay, N S, Pattison
openaire   +2 more sources

Cofactor Chemogenomics

2009
Cofactors are organic molecules, most of them originating from vitamins, that bind to enzymes making them able to catalyze defined reactions. A cofactor-based chemogenomics approach exploits the presence of a cofactor-binding domain to develop compound scaffolds tailored to mimic the cofactor and to replace it within target enzyme classes. As a result,
SINGH R, MOZZARELLI, Andrea
openaire   +2 more sources

An unexpected cofactor

Science, 2019
A mystery of bacterial chromosome segregation is explained by a nucleotide ...
openaire   +2 more sources

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