Results 31 to 40 of about 349,815 (226)
Non‐DNA‐binding cofactors enhance DNA‐binding specificity of a transcriptional regulatory complex
Molecular Systems Biology, 2011 Recruitment of cofactors to specific DNA sites is integral for specificity in gene regulation. As a model system, we examined how targeting and transcriptional control of the sulfur metabolism genes in Saccharomyces cerevisiae is governed by recruitment ...
Trevor Siggers +4 more
doaj +1 more source
Cell Genomics, 2022 Summary: Non-coding DNA variants (NCVs) impact gene expression by altering binding sites for regulatory complexes. New high-throughput methods are needed to characterize the impact of NCVs on regulatory complexes.
David Bray +11 more
doaj +1 more source
One diagonal texture or cofactor zero of the neutrino mass matrix
, 2013 In view of the recent measurement of nonzero $\theta_{13}$, we carry out a systematic study of a simple class of neutrino models that has one diagonal texture or cofactor zero in the mass matrix.
Liao, Jiajun +2 more
core +1 more source
Conformational Transitions Accompanying Oligomerization of Yeast Alcohol Oxidase, a Peroxisomal Flavoenzyme [PDF]
, 1999 Alcohol oxidase (AO) is a homo-octameric flavoenzyme which catalyzes methanol oxidation in methylotrophic yeasts. AO protein is synthesized in the cytosol and subsequently sorted to peroxisomes where the active enzyme is formed.
Boteva, R +6 more
core +3 more sources
Food Regime for Phenylketonuria: Presenting Complications and Possible Solutions
Journal of Multidisciplinary Healthcare, 2022 Sudipt Kumar Dalei, Nidhi Adlakha Regional Center for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, IndiaCorrespondence: Nidhi Adlakha Email nidhi.adlakha@rcb.res.inAbstract: In the category of rare inherited genetic disorders ...
Kumar Dalei S, Adlakha N
doaj
Pteridines, 2017 Pterins are widely conserved biomolecules that play essential roles in diverse organisms. First described as enzymatic cofactors in eukaryotic systems, bacterial pterins were discovered in cyanobacteria soon after.
Feirer Nathan, Fuqua Clay
doaj +1 more source
Microbiology Spectrum, 2022 Knowledge of the organizational and functional properties of hydrogen metabolism is pivotal to the construction of a framework supportive of a hydrogen-fueled low-carbon economy. Hydrogen metabolism relies on the mechanism of action of hydrogenases.
Pier Francesco Di Leonardo +3 more
doaj +1 more source
Cofactor and Cofactor Mimetics
Blood, 2019 Many natural enzymes need the assistance of protein cofactors to catalyze chemical reactions at a physiologically relevant speed and several of the enzymes that make up for the coagulation cascade are no exception in this regard. Notably, activated factors VII, IX and X display relatively poor enzymatic activity towards their respective macromolecular ...
openaire +1 more source
A computational framework to emulate the human perspective in flow cytometric data analysis [PDF]
, 2012 Background: In recent years, intense research efforts have focused on developing methods for automated flow cytometric data analysis. However, while designing such applications, little or no attention has been paid to the human perspective that is ...
AP Dempster +46 more
core +5 more sources
Study of the cofactor conditions: conditions of supercompatibility between phases
, 2013 The cofactor conditions, introduced in James and Zhang, are conditions of compatibility between phases in martensitic materials. They consist of three subconditions: i) the condition that the middle principal stretch of the transformation stretch tensor $
Chen, Xian +3 more
core +2 more sources