Results 71 to 80 of about 1,548,183 (362)
Annals of General PsychiatryBackground Nicotine use and nicotine use disorder (NUD) are the leading causes of preventable death in the United States. Persons with mental disorders (e.g., bipolar disorder) are differentially susceptible to nicotine use.
Serene Lee +11 more
doaj +1 more source
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
FEBS Letters, EarlyView.Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka +6 more
wiley +1 more source
A Framework of Defining, Modeling, and Analyzing Cognition Mechanisms [PDF]
arXiv, 2023 Cognition is a core part of and a common topic among philosophy of mind, psychology, neuroscience, AI, and cognitive science. Through a mechanistic lens, I propose a framework of defining, modeling, and analyzing cognition mechanisms. Firstly, appropriate terms are introduced and used in explanations related to the framework and within the definition ...
arxiv
Resolving Two Tensions in 4E Cognition Using Wide Computationalism [PDF]
, 2017 Recently, some authors have begun to raise questions about the potential unity of 4E (enactive, embedded, embodied, extended) cognition as a distinct research programme within cognitive science.
Deane, George +2 more
core +1 more source
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source
On the Notion of Cognition [PDF]
arXiv, 2003 We discuss philosophical issues concerning the notion of cognition basing ourselves in experimental results in cognitive sciences, especially in computer simulations of cognitive systems. There have been debates on the "proper" approach for studying cognition, but we have realized that all approaches can be in theory equivalent.
arxiv
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling
Nature Communications, 2019 Kleefstra syndrome is a neurodevelopmental disorder associated with hapoinsufficiency of the histone methyltransferase EHMT1. Here the authors show using induced pluripotent cells-derived neurons from patients that network dysfunction occurs and is due ...
Monica Frega +18 more
doaj +1 more source
Embodied cognition and temporally extended agency [PDF]
, 2018 According to radical versions of embodied cognition, human cognition and agency should be explained without the ascription of representational mental states.
Schlosser, Markus
core
Embodied cognitive ecosophy: the relationship of mind, body, meaning and ecology [PDF]
, 2017 The concept of embodied cognition has had a major impact in a number of disciplines. The extent of its consequences on general knowledge and epistemology are still being explored.
Aizawa Ken. +31 more
core +1 more source
Conscious cognitive effort in cognitive control
WIREs Cognitive Science, 2022 Cognitive effort is thought to be familiar in everyday life, ubiquitous across multiple variations of task and circumstance, and integral to cost/benefit computations that are themselves central to the proper functioning of cognitive control. In particular, cognitive effort is thought to be closely related to the assessment of cognitive control’s costs.
openaire +3 more sources