Results 71 to 80 of about 2,122,742 (336)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Exploring the electrophysiological correlates of the default-mode network with intracerebral EEG

Frontiers in Systems Neuroscience, 2010
While functional imaging studies allow for a precise spatial characterization of resting state networks, their neural correlates and thereby their fine-scale temporal dynamics remain elusive.
Karim Jerbi, Karim Jerbi, Juan R Vidal, Juan R Vidal, Tomas Ossandon, Tomas Ossandon, Sarang S Dalal, Sarang S Dalal, Julien Jung, Julien Jung, Dominique Hoffmann, Lorella Minotti, Olivier Bertrand, Olivier Bertrand, Philippe Kahane, Jean-Philippe Lachaux, Jean-Philippe Lachaux   +16 more
doaj   +1 more source

Poetic Metaphors and Embodied Cognition A Potential Pathway of Mind Development [PDF]

, 2023
Yanzhu Fan
openalex   +1 more source

Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease

JAMA Neurology, 2019
Key Points Question Is cognitive decline associated with amyloid-β or tau tangles accumulation? Findings In this cohort study that included 60 normal older adults with repeated positron emission tomography measures, the rate of tau accumulation in the ...
Bernard J. Hanseeuw, Bernard J. Hanseeuw, R. Betensky, H. I. Jacobs, H. I. Jacobs, A. Schultz, J. Sepulcre, J. Becker, Danielle M. Cosio, Michelle E. Farrell, Y. Quiroz, Elizabeth C. Mormino, Elizabeth C. Mormino, Rachel F Buckley, Rachel F Buckley, Rachel F Buckley, K. Papp, K. Papp, Rebecca Amariglio, Rebecca Amariglio, Ilse Dewachter, Ilse Dewachter, A. Ivanoiu, A. Ivanoiu, W. Huijbers, W. Huijbers, T. Hedden, G. Marshall, G. Marshall, J. Chhatwal, D. Rentz, D. Rentz, R. Sperling, R. Sperling, Keith A. Johnson, Keith A. Johnson   +35 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Strain-specific pre-existing immunity: A key to understanding the role of chronic Toxoplasma infection in cognition and Alzheimer's diseases?

, 2022
Jianchun Xiao, Alena Savonenko, Robert H. Yolken   +2 more
openalex   +1 more source

Cohabitation: Computation at 70, Cognition at 20 [PDF]

, 2006
Zenon Pylyshyn cast cognition's lot with computation, stretching the Church/Turing Thesis to its limit: We had no idea how the mind did anything, whereas we knew computation could do just about everything. Doing it with images would be like doing it with
Harnad, Stevan
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Dissecting task-based fMRI activity using normative modelling: an application to the Emotional Face Matching Task

Communications Biology
Functional neuroimaging has contributed substantially to understanding brain function but is dominated by group analyses that index only a fraction of the variation in these data.
Hannah S. Savage, Peter C. R. Mulders, Philip F. P. van Eijndhoven, Jasper van Oort, Indira Tendolkar, Janna N. Vrijsen, Christian F. Beckmann, Andre F. Marquand   +7 more
doaj   +1 more source

Generating normative data from web-based administration of the Cambridge Neuropsychological Test Automated Battery using a Bayesian framework

Frontiers in Digital Health
IntroductionNormative cognitive data can distinguish impairment from healthy cognitive function and pathological decline from normal ageing. Traditional methods for deriving normative data typically require extremely large samples of healthy participants,
Elizabeth Wragg, Caroline Skirrow, Caroline Skirrow, Pasquale Dente, Jack Cotter, Peter Annas, Peter Annas, Milly Lowther, Milly Lowther, Rosa Backx, Jenny Barnett, Jenny Barnett, Fiona Cree, Jasmin Kroll, Francesca Cormack   +14 more
doaj   +1 more source