Results 41 to 50 of about 248,097 (199)

The association between gray matter volume in the hippocampal subfield and antidepressant efficacy mediated by abnormal dynamic functional connectivity

Scientific Reports
An abnormality of structures and functions in the hippocampus may have a key role in the pathophysiology of major depressive disorder (MDD). However, it is unclear whether structure factors of the hippocampus effectively impact antidepressant responses ...
Changxiao Kuai, Jiayong Pu, Donglin Wang, Zhonglin Tan, Yan Wang, Shao-Wei Xue   +5 more
doaj   +1 more source

Design of the PERSPECTIVE study: PERsonalized SPEeCh Therapy for actIVE conversation in Parkinson’s disease (randomized controlled trial)

Trials, 2022
Objective To evaluate the effectiveness of personalized and home-based speech therapy on quality of life, intelligibility, and social participation for people with Parkinson’s disease (PD) who have a reduced intelligibility of speech.
J. J. L. Maas, N. M. De Vries, B. R. Bloem, J. G. Kalf   +3 more
doaj   +1 more source

The effects of impulsivity and proactive inhibition on reactive inhibition and the go process: insights from the stop signal task of vocal and manual responses

Frontiers in Human Neuroscience, 2015
This study measured proactive and reactive response inhibition and their relationships with self-reported impulsivity. We examined the domains of both vocal and manual responding using a stop signal task (SST) with two stop probabilities: high and low ...
Leidy Janeth Castro-Meneses, Leidy Janeth Castro-Meneses, Blake Warren Johnson, Paul Fredrick Sowman, Paul Fredrick Sowman   +4 more
doaj   +1 more source

Editorial: Cognition in Mood Disorders

Frontiers in Psychiatry, 2020
Mood disorders are common, complex, and one of the main causes of morbidity worldwide (1). There has been an increasing recognition that cognitive dysfunction is a central aspect of most mood disorders, as well as being closely related to the functional impairment that these disorders commonly cause (2, 3).
Mayowa Oyesanya, Mayowa Oyesanya, Catherine J. Harmer, Catherine J. Harmer, Allan H. Young   +4 more
openaire   +4 more sources

Cholinergic Receptors in Cognitive Disorders [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1986
Abstract:Cholinergic receptors (muscarinic subtypes M1 and M2, and putative nicotinic binding) have been examined in the hippocampus obtained at autopsy from a variety of patients with cognitive disorders (Alzheimer's, Parkinson's, and Huntington's diseases, Down's Syndrome and alcoholic dementia) and compared with neurologically normal controls and ...
Perry EK, Perry RH, Smith CJ, Purohit D, Bonham J, Dick DJ, Candy JM, Edwardson JA, Fairbairn A   +8 more
openaire   +2 more sources

Asymmetric Differences in the Gray Matter Volume and Functional Connections of the Amygdala Are Associated With Clinical Manifestations of Alzheimer’s Disease

Frontiers in Neuroscience, 2020
ObjectiveAsymmetry is a subtle but pervasive aspect of the human brain, which may be altered in several neuropsychiatric conditions. Magnetic resonance imaging (MRI) studies have reported that cerebral structural asymmetries are altered in Alzheimer’s ...
Xingqi Wu, Xingqi Wu, Yue Wu, Yue Wu, Zhi Geng, Zhi Geng, Shanshan Zhou, Shanshan Zhou, Shanshan Zhou, Ling Wei, Ling Wei, Ling Wei, Gong-Jun Ji, Gong-Jun Ji, Gong-Jun Ji, Yanghua Tian, Yanghua Tian, Yanghua Tian, Kai Wang, Kai Wang, Kai Wang, Kai Wang   +21 more
doaj   +1 more source

Exploring the levodopa-paradox of freezing of gait in dopaminergic medication-naïve Parkinson’s disease populations

npj Parkinson's Disease, 2023
The relationship between dopaminergic treatment and freezing of gait (FOG) in Parkinson’s disease (PD) is complex: levodopa is the most effective symptomatic treatment for FOG, but long-term pulsatile levodopa treatment has also been linked to an ...
Jamie A. F. Jansen, Tamine T. C. Capato, Sirwan K. L. Darweesh, Egberto R. Barbosa, Rogier Donders, Bastiaan R. Bloem, Jorik Nonnekes   +6 more
doaj   +1 more source

Helping children with reading difficulties: some things we have learned so far

npj Science of Learning, 2017
A substantial proportion of children struggle to learn to read. This not only impairs their academic achievement, but increases their risk of social, emotional, and mental health problems.
Genevieve McArthur, Anne Castles
doaj   +1 more source

Disorders of Visuo-spatial Cognition

Neurocase, 2005
Disorders of visuo-spatial ...
Humphreys, G, Husain, M, Farné, A, Rorden, C, Bartolomeo, Paolo   +4 more
openaire   +4 more sources

Cognitive style in bipolar disorder [PDF]

British Journal of Psychiatry, 2005
BackgroundAbnormalities of cognitive style in bipolar disorder are of both clinical and theoretical importance.AimsTo compare cognitive style in people with affective disorders and in healthy controls.MethodSelf-rated questionnaires were administered to 118 individuals with bipolar I disorder, 265 with unipolar major recurrent depression and 268 ...
Jones L, Scott J, Haque S, Gordon-Smith K, Heron J, Caesar S, Cooper C, Forty L, Hyde S, Lyon L, Greening J, Sham P, Farmer A, McGuffin P, Jones I, Craddock N   +15 more
openaire   +5 more sources