Results 51 to 60 of about 280,147 (323)

Cognitive disorders: A question of misattribution [PDF]

Current Biology, 1999
A recent study indicates that schizophrenia patients are prone to auditory hallucinations because they have difficulty recognising their 'inner speech' as their own, and consequently tend to misattribute it to an external source.
Alexandra J. Richardson, John F. Stein
openaire   +3 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Analyzing the Effect of Data Impurity on the Detection Performances of Mental Disorders [PDF]

arXiv, 2023
The primary method for identifying mental disorders automatically has traditionally involved using binary classifiers. These classifiers are trained using behavioral data obtained from an interview setup. In this training process, data from individuals with the specific disorder under consideration are categorized as the positive class, while data from
arxiv  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Males are more sensitive to reward and less sensitive to loss than females among people with internet gaming disorder: fMRI evidence from a card-guessing task

BMC Psychiatry, 2020
Background Many studies have found an interesting issue in the Internet gaming disorder (IGD): males are always observed to be the majority. However, there are little research to exploring the differences in the neural mechanisms between males and ...
Jialin Zhang, Yan Hu, Ziliang Wang, Min Wang, Guang-Heng Dong   +4 more
doaj   +1 more source

Design of the PERSPECTIVE study: PERsonalized SPEeCh Therapy for actIVE conversation in Parkinson’s disease (randomized controlled trial)

Trials, 2022
Objective To evaluate the effectiveness of personalized and home-based speech therapy on quality of life, intelligibility, and social participation for people with Parkinson’s disease (PD) who have a reduced intelligibility of speech.
J. J. L. Maas, N. M. De Vries, B. R. Bloem, J. G. Kalf   +3 more
doaj   +1 more source

HDL and cognition in neurodegenerative disorders [PDF]

Neurobiology of Disease, 2014
High-density lipoproteins (HDLs) are a heterogeneous group of lipoproteins composed of various lipids and proteins. HDL is formed both in the systemic circulation and in the brain. In addition to being a crucial player in the reverse cholesterol transport pathway, HDL possesses a wide range of other functions including anti-oxidation, anti-inflammation,
Shaowu Cheng, Dustin Chernick, Zhe Wang, Ling Li, David A. Hottman   +4 more
openaire   +4 more sources

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

The Role of Slow Speech Amplitude Envelope for Speech Processing and Reading Development

Frontiers in Psychology, 2017
This study examined the putative link between the entrainment to the slow rhythmic structure of speech, speech intelligibility and reading by means of a behavioral paradigm.
Paula Ríos-López, Monika T. Molnar, Mikel Lizarazu, Marie Lallier   +3 more
doaj   +1 more source

State-dependent changes of connectivity patterns and functional brain network topology in Autism Spectrum Disorder [PDF]

Neuropsychologia. 2012 Oct 5;50(14):3653-3662, 2012
Anatomical and functional brain studies have converged to the hypothesis that Autism Spectrum Disorders (ASD) are associated with atypical connectivity. Using a modified resting-state paradigm to drive subjects' attention, we provide evidence of a very marked interaction between ASD brain functional connectivity and cognitive state.
arxiv   +1 more source