Results 91 to 100 of about 251,547 (296)

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel   +5 more
wiley   +1 more source

No interaction between tDCS current strength and baseline performance: a conceptual replication [PDF]

open access: yes, 2009
Several recent studies have reported non-linear effects of transcranial direct current stimulation (tDCS), which has been attributed to an interaction between the stimulation parameters (e.g., current strength, duration) and the neural state of the ...
Gemma Learmonth   +76 more
core   +3 more sources

Strengthening Attachment-Based Therapies: A Case for Cognitive Bias Modification? [PDF]

open access: yesJournal of the American Academy of Child & Adolescent Psychiatry, 2019
A recent article published in the Journal describes the effectiveness of attachment-based family therapy in decreasing suicidal ideation and depressive symptoms in adolescents. 1Because insecure attachment is a transdiagnostic risk factor in the development of psychological problems in children and adolescents, improving attachment relationships is an ...
Verhees, Martine W.FT.   +2 more
openaire   +3 more sources

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz   +25 more
wiley   +1 more source

Combining Web-Based Attentional Bias Modification and Approach Bias Modification as a Self-Help Smoking Intervention for Adult Smokers Seeking Online Help: Double-Blind Randomized Controlled Trial

open access: yesJMIR Mental Health, 2020
BackgroundAutomatically activated cognitive motivational processes such as the tendency to attend to or approach smoking-related stimuli (ie, attentional and approach bias) have been related to smoking behaviors.
Wen, Si   +6 more
doaj   +1 more source

Emotion recognition training using composite faces generalises across identities but not all emotions [PDF]

open access: yes, 2017
Many cognitive bias modification (CBM) tasks use facial expressions of emotion as stimuli. Some tasks use unique facial stimuli, while others use composite stimuli, given evidence that emotion is encoded prototypically.
Dalili, Michael   +3 more
core   +2 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Working memory load elicits attentional bias to threat [PDF]

open access: yes, 2014
Anxious individuals tend to show attentional bias to threats and dangers; this is usually in-terpreted as a specific bias in threat-processing. However, they also tend to show general working memory and cognitive control impairments. We hypothesised that
Booth, Robert, Sharma, Dinkar
core  

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Effectiveness of two web-based cognitive bias modification interventions targeting approach and attentional bias in gambling problems: study protocol for a pilot randomised controlled trial

open access: yesTrials, 2017
Background Disordered gamblers have phenotypical and pathological similarities to those with substance use disorders (SUD), including exaggerated automatic cognitive processing of motivationally salient gambling cues in the environment (i.e., attentional
Marilisa Boffo   +4 more
doaj   +1 more source

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