Results 51 to 60 of about 11,992,242 (255)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Proposing a new focus for the study of natural and artificial cognitive systems [PDF]

, 2002
In the study of systems the function of the system is often a good hint to how it works. In the following paper I would like to suggest that in studying or modeling a cognitive system our pre-knowledge of their functions should be treated carefully.
Hershberg, Uri
core  

Blinking predicts enhanced cognitive control

, 2013
Contains fulltext : 129957.pdf (Publisher’s version ) (Closed access)Recent models have suggested an important role for neuromodulation in explaining trial-to-trial adaptations in cognitive control.
Van der Haegen, LiseUGent002003019280802000158064976016154208FADF1ABC-F0ED-11E1-A9DE-61C894A0A6B4, Notebaert, Wim, van Bochove, MarliesUGent0000914364428020007705789753270369062760462E-F0EE-11E1-A9DE-61C894A0A6B4, Verguts, Tom, Bochove, M.E. van, van Bochove, Marlies, Verguts, TomPP02PP558010015366970000-0002-7783-4754F62E687E-F0ED-11E1-A9DE-61C894A0A6B4, Notebaert, W., Verguts, T., Van der Haegen, Lise, Notebaert, WimPP028010017967790000-0002-7281-7816F6EAE544-F0ED-11E1-A9DE-61C894A0A6B4, Haegen, L. Van der   +11 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Differentiating the functional contributions of resting connectivity networks to memory decision-making : fMRI support for multi-stage control processes [PDF]

, 2015
Neural substrates of memory control are engaged when participants encounter unexpected mnemonic stimuli (e.g., a new word when told to expect an old word).
Cavin, Ian, O'Connor, Akira Robert, Mill, Ravi Dev, Akira O'Connor (708766), Ravi Mill (708768), Ian Cavin (708767)   +5 more
core   +1 more source

Transient and selective effects of acute exercise intensity on response inhibition: an EEG study

Frontiers in Human Neuroscience
Acute aerobic exercise can transiently influence cognitive control, but how exercise intensity and recovery timing shape response inhibition and its neural correlates remains insufficiently understood.
Masaki Takayose, Masaki Takayose, Ryo Koshizawa, Kazuma Oki, Christina Thunberg, René J. Huster   +5 more
doaj   +1 more source

The error‐related negativity as a neuromarker of risk or resilience in young children

Brain and Behavior, 2021
Introduction The error‐related negativity (ERN) is a neural response that reflects error monitoring. Contradictorily, an enlarged (more negative) ERN has been cited as both a risk factor and a protective factor, which hinders its utility as a predictive ...
Jamie M. Lawler, Jessica Hruschak, Kristin Aho, Yanni Liu, Ka I. Ip, Renee Lajiness‐O’Neill, Katherine L. Rosenblum, Maria Muzik, Kate D. Fitzgerald   +8 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The role of cognitive processes in sleep disturbance: a comparison of Japanese and English university students [PDF]

, 2002
The present study investigated the role of cognitive processes in the maintenance of clinically significant sleep disturbance across two cultures. A questionnaire was administered to 60 Japanese and 60 English university students to assess the presence ...
Bird, C.M., Harvey, Allison G., Gregory, Alice M., Harvey, A.G., Bird, Chris, Gregory, A.M.   +5 more
core   +1 more source