Results 61 to 70 of about 989,086 (340)

Postoperative Cognitive Decline [PDF]

American Journal of Biomedical Science & Research, 2019
Due to a combination of advancing medical technology and the increasing age of the adult population, more adults are pursuing surgical intervention, particularly elective surgery, than ever before. Postoperative cognitive decline (POCD) describes either a transient or chronic change in cognitive function that comes as a result of anesthesia or surgical
Dawson Hedges, Thomas J. Farrer, Erin D. Bigler, Ramona O. Hopkins   +3 more
openaire   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

The Heterogeneity of Longitudinal Cognitive Decline in Euthymic Bipolar I Disorder With Clinical Characteristics and Functional Outcomes

Frontiers in Psychiatry, 2021
We characterized the heterogeneity and risk factors of cognitive decline in euthymic bipolar disorder (BD), and their magnitude of associations with subjective daily functions.
Wen-Yin Chen, Wen-Yin Chen, Ming-Chyi Huang, Ming-Chyi Huang, Ya-Chin Lee, Chiao-Erh Chang, Shih-Ku Lin, Shih-Ku Lin, Chih Chiang Chiu, Chih Chiang Chiu, Hsing-Cheng Liu, Hsing-Cheng Liu, Chian-Jue Kuo, Chian-Jue Kuo, Shih-Han Weng, Po-Yu Chen, Po-Yu Chen, Po-Hsiu Kuo, Po-Hsiu Kuo, Po-Hsiu Kuo   +19 more
doaj   +1 more source

The Contribution of Blood Serum Biomarkers to the Prediction of Cognitive Decline by fMRI and Apolipoprotein-E in Healthy Older Adults [PDF]

, 2012
Biomarkers are a promising approach to the prediction and early intervention of Alzheimer\u27s disease. We demonstrated that cortical functional MRI (fMRI) activation during a semantic memory task and apolipoprotein-E ?4 allele inheritance (APOE?4 ...
Durgerian, Sally, Nielson, Kristy A., Rao, Stephen M., Seidenberg, Michael, Smith, J. Carson, Sugarman, Michael, Woodard, John L.   +6 more
core   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Long-Term Increase in Cholesterol Is Associated With Better Cognitive Function: Evidence From a Longitudinal Study

Frontiers in Aging Neuroscience, 2021
Background: Higher visit-to-visit cholesterol has been associated with cognitive decline. However, the association between long-term increase or decrease in cholesterol and cognitive decline remains unclear.Methods: A total of 4,915 participants aged ≥45
Huamin Liu, Lianwu Zou, Rui Zhou, Minyi Zhang, Shanyuan Gu, Jiazhen Zheng, Daniel Nyarko Hukportie, Keyi Wu, Zhiwei Huang, Zelin Yuan, Xianbo Wu   +10 more
doaj   +1 more source

Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ [PDF]

, 2017
In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline.
McCleery, Jenny, Quinn, Terence J.
core   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis [PDF]

, 2018
Evidence suggests that affective problems, such as depression and anxiety, increase risk for late-life dementia. However, the extent to which affective problems influence cognitive decline, even many years prior to clinical diagnosis of dementia, is not ...
Gaysina, D, John, A, Patel, U, Richards, M, Rusted, J   +4 more
core   +2 more sources

CKD Associates with Cognitive Decline [PDF]

Journal of the American Society of Nephrology, 2009
Cognitive impairment and chronic kidney disease (CKD) will become increasingly prevalent in the aging US population. Although evidence exists that CKD is a risk factor for cognitive decline, longitudinal studies are limited and largely have excluded ethnically diverse populations.
Minesh, Khatri, Thomas, Nickolas, Yeseon P, Moon, Myunghee C, Paik, Tatjana, Rundek, Mitchell S V, Elkind, Ralph L, Sacco, Clinton B, Wright   +7 more
openaire   +2 more sources