Results 41 to 50 of about 438,111 (313)
Cognitive decline in people with mild dementia during COVID-19 pandemic
, 2023 reservedBackground: restrictive measures adopted to prevent the spread of COVID-19 infection resulted in pre-existing neuropsychiatric symptoms and cognitive worsening in people with MCI and dementia in the first year of pandemic.
MARIOTTI, MARTINA
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Alzheimer’s Research & Therapy, 2021 Background Comprehensive testing of cognitive functioning is standard practice in studies of Alzheimer disease (AD). Short-form tests like the Montreal Cognitive Assessment (MoCA) use a “sampling” of measures, administering key items in a shortened ...
Jason Hassenstab +7 more
doaj +1 more source
Cognitive decline in an older physician [PDF]
Canadian Medical Association Journal, 2015 A 78-year-old right-handed physician with hypertension and dyslipidemia presented to the emergency department with progressive memory impairment and acute onset of left-sided weakness. His only medication was daily low-dose acetylsalicylic acid.
Gregory S, Day +2 more
openaire +2 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Informant reported cognitive decline in older adults [PDF]
, 2017 Objectives: Gaining an informant’s perspective on cognitive decline has become an increasingly popular, and recommended practice, in the assessment of dementia. However, concern regarding the accuracy of such reports has been documented.
Morrell, L.
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
, 2007 Objective: To investigate in a longitudinal cohort of people with Alzheimer's disease whether taking antipsychotics is associated with more rapid cognitive deterioration.
Walker, A.E. +6 more
core +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source