Results 31 to 40 of about 438,111 (313)
Steeper memory decline after COVID-19 lockdown measures
Alzheimer’s Research & Therapy, 2023 Background During COVID-19 lockdown measures, memory clinic patients reported worries for faster cognitive decline, due to loss of structure and feelings of loneliness and depression. We aimed to investigate the impact of the COVID-19 lockdown on rate of
Els D. Bakker +7 more
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Alzheimer’s Research & Therapy, 2023 Background Subjective cognitive decline (SCD) is a risk factor for Alzheimer’s disease (AD); however, the rates of cognitive decline are variable according to underlying pathologies and biomarker status.
Yun Jeong Hong +8 more
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Cognition Enhancers in Age-Related Cognitive Decline [PDF]
Drugs & Aging, 1996 A review of recently published studies on the effect of cognition enhancers in non-demented human study participants is presented. The heterogeneity of the therapeutic target, age-associated cognitive decline, can be improved by separately treating groups in whom age-extrinsic factors may underlie cognitive pathology.
Riedel, Wim J., Jolles, Jellemer
openaire +3 more sources
BMJ Open, 2019 Introduction Managing medication regimens is one of the most complex and burdensome tasks performed by older people, and can be prone to errors. People living with dementia may require medication administration assistance from formal and informal ...
Sarah N Hilmer +10 more
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Isolated Cognitive Decline in Neurologically Stable Patients with Multiple Sclerosis
Diagnostics, 2021 (1) Background: Cognitive deterioration is an important marker of disease activity in multiple sclerosis (MS). It is vital to detect cognitive decline as soon as possible. Cognitive deterioration can take the form of isolated cognitive decline (ICD) with
Jiri Motyl +11 more
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Longitudinal associations between physical and cognitive performance among community-dwelling older adults. [PDF]
PLoS ONE, 2015 To assess the directionality of the association between physical and cognitive decline in later life, we compared patterns of decline in performance across groups defined by baseline presence of cognitive and/or physical impairment [none (n = 217 ...
Magdalena I Tolea +2 more
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Demand Coupling Drives Neurodegeneration: A Model of Age-Related Cognitive Decline and Dementia
Cells, 2022 The societal burden of Alzheimer’s Disease (AD) and other major forms of dementia continues to grow, and multiple pharmacological agents directed towards modifying the pathological “hallmarks” of AD have yielded disappointing results.
Josh Turknett, Thomas R. Wood
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Cognitive decline and the neighborhood environment [PDF]
Annals of Epidemiology, 2015 Little research has looked beyond individual factors to consider the influence of the neighborhood environment on cognitive function. A greater density of physical resources (e.g., recreational centers and parks) and institutional resources (e.g., community centers) may buffer cognitive decline by offering opportunities for physical activity and social
Philippa J, Clarke +4 more
openaire +2 more sources
BMC Geriatrics, 2019 Background Vitamin D supplement use is recommended best practice in residential aged care facilities (RACFs) for the prevention of falls, however has experienced delays in uptake.
Pippy Walker +3 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source