Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
Overactive Glutamatergic Basal Forebrain: Compensatory or Causal Mechanism in Cognitive Disorders. [PDF]
Calderon DP, Goldstein PA.
europepmc +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
A user's guide for the International Classification of Cognitive Disorders in Epilepsy. [PDF]
Hermann B +8 more
europepmc +1 more source
Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio +3 more
wiley +1 more source
Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The "Village Bondeko" Center, In Kinshasa. [PDF]
Masamba GR +11 more
europepmc +1 more source
Effect of long-term treatment with memantine on mortality in patients with major cognitive disorders: A systematic review and meta-analysis. [PDF]
Zolnowski-Kolp V +4 more
europepmc +1 more source
Immune Profiling in Early Cognitive Disorders (IMPRINT) study protocol: a longitudinal cohort study exploring biomarkers of inflammation in early dementia with Lewy bodies and Alzheimer's disease, as part of the Dementias Platform UK. [PDF]
Crook H +16 more
europepmc +1 more source

