Results 51 to 60 of about 706,522 (143)

Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline–Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora

Molecules
Previous studies have revealed the microbial metabolism of dietary choline in the gut, leading to its conversion into trimethylamine (TMA). Polymethoxyflavones (PMFs), exemplified by tangeretin, have shown efficacy in mitigating choline-induced ...
Yu Cao, Changlong Leng, Kuan Lin, Youwei Li, Meiling Zhou, Mei Zhou, Xiji Shu, Wei Liu   +7 more
doaj   +1 more source

HIV-1 Vpr activates microglia by upregulating m6A modification through ubiquitin-proteasome pathway-mediated degradation of the demethylase ALKBH5

Virulence
HIV-1 infection activates microglia and triggers neuroinflammation, which is the primary cause of HIV-associated neurological complications. Our previous study demonstrated that HIV-1 infection upregulates m6A modification in microglia, and in this study
Qian Peng, Weiling Li, Feng Qian, YinYing Zhu, Song Hu, Yingying Shi, Yiyuan Xia, Wei Liu, Xiji Shu, Pin Wan, Yuchen Liu, Binlian Sun   +11 more
doaj   +1 more source

Unstable functional brain states and reduced cerebro-cerebellar modularity in elderly individuals with subjective cognitive decline

NeuroImage
The preclinical stage of Alzheimer's Disease (AD) holds great potential for intervention, therefore, it is crucial to elucidate the neural mechanisms underlying the progression of subjective cognitive decline (SCD).
Wuhai Tao, Xiaojie Lu, Shuaike Yuan, Peixuan Ye, Zhanjun Zhang, Qing Guan, Hehui Li   +6 more
doaj   +1 more source

A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for migraine

The Journal of Headache and Pain
Background Migraine is a common neurological disorder with a strong genetic component. Despite the identification of over 100 loci associated with migraine susceptibility through genome-wide association studies (GWAS), the underlying causative genes and ...
Jianxiong Gui, Xiaoyue Yang, Chen Tan, Lingman Wang, Linxue Meng, Ziyao Han, Jie Liu, Li Jiang   +7 more
doaj   +1 more source

Effectiveness of a home-based, post-discharge early intervention program for very preterm infants in reducing parental stress: a randomized controlled trial

BMC Public Health
Background This study aims to evaluate the impact of a home-based, post-discharge early intervention (EI) program on reducing parental stress levels in families with preterm infants born between 28+ 0 and 31+ 6 weeks gestational age. Methods A randomized
Juan Fan, Ruiyun He, Shasha He, Mei Yang, Xiaojun Tao, Mei Zhou, Xiong Gao, Weihong Yu, Jianhui Wang   +8 more
doaj   +1 more source

Rehabilitation for spinal muscular atrophy patients in China: a national cross-sectional study

Orphanet Journal of Rare Diseases
Background The management of Spinal Muscular Atrophy (SMA) requires a multidisciplinary treatment approach, wherein rehabilitation constitutes an integral element.
Duan Wang, Ting Zhang, Yi Li, Jiayu Liu, Yongzhu Jia, Nong Xiao   +5 more
doaj   +1 more source

Signaling Molecules and Diagnosis of Cognitive Disorders: Current State and Prospects. [PDF]

Int J Mol Sci
Kvetnoy I, Kheyfets O, Safaniev L, Kheifets V, Mironova E, Kvetnaia T, Mazzoccoli G, Prashchayeu K, Gavrilova A.   +8 more
europepmc   +1 more source

Cognitive Disorder [PDF]

, 2020
openaire   +2 more sources

The international society of vascular behavioural and cognitive disorders: highlights from VasCog 2025 in the UK. [PDF]

Cereb Circ Cogn Behav
Marseglia A, Carare RO, Teeling JL, Hilal S, Cai VY, Chander R, Chabriat H, Gustafson D, Hainsworth AH, Hansra GK, James SN, Low A, Ottoy J, Saito S, Ter Telgte A, van den Brink H, Wolters FJ, Vemuri P.   +17 more
europepmc   +1 more source

Periodontitis and Tooth Loss Are Associated With Higher Risks of Cognitive Disorders: A Systematic Umbrella Meta-Analysis. [PDF]

Clin Exp Dent Res
Qadir BH, Mahmood MK, Amin YMM, Kurda HA, Rasheed TA, Noori AH, Noori ZF, Abdulghafor MA, Fadhil HNM, Fatih MT, Tardivo D, Tassery H, Lan R.   +12 more
europepmc   +1 more source