Results 11 to 20 of about 325,274 (194)

Clinical Practice Guideline on Non-pharmacological Interventions for Older Adults with Cognitive Dysfunction: Physical Activity [PDF]

open access: yesZhongguo quanke yixue, 2023
Cognitive dysfunction refers to the functional impairment in one or more cognitive domains, mostly occurs in older adults. Cognitive dysfunction can commonly be divided into subjective cognitive decline (SCD), mild cognitive impairment (MCI) and dementia,
China Gerontological Nursing Alliance, Xiang Ya Nursing School (Xiangya Oceanwide Health Management Research Institute of Central South University), Xiangya Hospital Central South University (National Clinical Research Center for Geriatric Disorders), Beijing Hospital (National Center for Gerontology, National Clinical Research Center for Geriatric Disorders), ZENG Xianmei, HU Mingyue, FENG Hui
doaj   +1 more source

Predictive Value of Sensory Dysfunction in Early Recognition and Treatment of Cognitive Dysfunction: a Review [PDF]

open access: yesZhongguo quanke yixue, 2022
The initial symptoms of cognitive dysfunction disease are insidious, and most of the cognitive dysfunction diseases will be in the stage of dementia with no effective treatment when the symptoms are discovered.
Yunyun MA, Yulei SONG, Mengmeng WANG, Xiao LIANG, Xueqing ZHANG, Guihua XU, Dandan DU, Yamei BAI
doaj   +1 more source

Molecular Mechanisms in Pentanucleotide Repeat Diseases

open access: yesCells, 2022
The number of neurodegenerative diseases resulting from repeat expansion has increased extraordinarily in recent years. In several of these pathologies, the repeat can be transcribed in RNA from both DNA strands producing, at least, one toxic RNA repeat ...
Joana R. Loureiro   +3 more
doaj   +1 more source

Gene Network Mechanism of Zhilong Huoxue Tongyu Capsule in Treating Cerebral Ischemia–Reperfusion

open access: yesFrontiers in Pharmacology, 2022
Objective: To investigate the effect of Zhilong Huoxue Tongyu capsule (ZLH) in the treatment of cerebral ischemia–reperfusion injury and determine the underlying molecular network mechanism.Methods: The treatment effect of Zhilong Huoxue Tongyu capsule ...
Na Li   +5 more
doaj   +1 more source

A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology

open access: yesFrontiers in Pharmacology, 2022
Purpose: Diabetic retinopathy (DR) is a serious complication of diabetes mellitus, which nearly happens to all the diabetic sufferers. This study aims to identify the preliminary molecular regulation involved in the therapeutic efficacy of astragaloside ...
Zhi-Hao Zhao   +9 more
doaj   +1 more source

Salidroside attenuates HALI via IL-17A-mediated ferroptosis of alveolar epithelial cells by regulating Act1-TRAF6-p38 MAPK pathway

open access: yesCell Communication and Signaling, 2022
Plain English summary Oxygen inhalation has been widely used in the treatment of some diseases caused by hypoxia. This often leads people to mistakenly believe that oxygen inhalation is beneficial without harm.
Baoyue Guo   +11 more
doaj   +1 more source

Diagnosis and Management of Cognitive Dysfunction In Systemic Lupus Erythematosus Patients

open access: yesClinical and Research Journal in Internal Medicine, 2022
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with diverse clinical manifestations. One of the frequent manifestations of SLE is cognitive dysfunction. Cognitive dysfunction is a hidden and often undiagnosed manifestation of SLE but
Perdana Aditya Rahman   +3 more
doaj   +1 more source

Clinical associations of cognitive dysfunction in systemic lupus erythematosus

open access: yesLupus Science and Medicine, 2023
Objective Cognitive dysfunction in SLE is common, but clinical risk factors are poorly understood. This study aims to explore the associations of cognitive dysfunction in SLE with disease activity, organ damage, biomarkers and medications.Methods We ...
Rangi Kandane-Rathnayake   +6 more
doaj   +1 more source

Scutellarin protects cortical neurons against neonatal hypoxic‐ischemic encephalopathy injury via upregulation of vascular endothelial growth factor

open access: yesIbrain, 2022
Neonatal hypoxic‐ischemic encephalopathy (NHIE) causes devastating cerebral damage and neurological deficits that seldom have effective therapies. This study aimed to explore the mechanisms underlying the therapeutic efficacy of Scutellarin in NHIE. NHIE
Yu Zou   +4 more
doaj   +1 more source

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