Results 21 to 30 of about 552,457 (237)

Moderating Effects of Cortisol on Neural-Cognitive Association in Cognitively Normal Elderly Subjects

open access: yesFrontiers in Aging Neuroscience, 2017
Cortisol homeostasis is important for healthy brain and cognitive aging. The aim of the current study is to investigate the role of serum cortisol levels in the relationship between regional brain volumes and cognitive processing speed in a group of ...
Way K. W. Lau   +9 more
doaj   +1 more source

Evaluation and significance of cognitive dysfunction after cerebrovascular disease with convalescent rehabilitation. Assessment based on FIM, MMSE and HDS-R [PDF]

open access: yesBalneo and PRM Research Journal
To analyze the effectiveness of rehabilitation for patients with cognitive dysfunction after cerebrovascular disease at a rehabilitation hospital. 200 patients with cerebrovascular diseases who underwent rehabilitation were divided into two groups: 128 ...
Katsuo Usuda   +14 more
doaj   +1 more source

CA3 Induces Apoptosis of Hepatocellular Carcinoma HepG2 Cells and Related Mechanism

open access: yesZhongliu Fangzhi Yanjiu, 2020
Objective To investigate the effect of CA3(CIL56) on the proliferation and apoptosis of hepatocellular carcinoma HepG2 cells and its mechanism. Methods HepG2 cells were cultured in vitro and treated with different concentrations of CA3 (0, 0.25, 0.5, 1.0,
ZHANG Shuwen   +3 more
doaj   +1 more source

Cognitive Dysfunction in Multiple Sclerosis [PDF]

open access: yesFrontiers in Neurology, 2012
In Multiple Sclerosis (MS) prevalence studies of community and clinical samples, indicate that 45-60% of patients are cognitively impaired. These cognitive dysfunctions have been traditionally described as heterogeneous, but more recent studies suggest that there is a specific pattern of MS-related cognitive dysfunctions.
Joana eGuimarães   +3 more
openaire   +3 more sources

The Role of Gut Microbiota in Mice With Bile Duct Ligation-Evoked Cholestatic Liver Disease-Related Cognitive Dysfunction

open access: yesFrontiers in Microbiology, 2022
The pathogenesis of Hepatic Encephalopathy (HE) is complex and multifactorial. The development of metagenomics sequencing technology led to show the significant role of gut microbiota in the pathogenesis of cognitive dysfunction, which paved the way for ...
Bowen Yang   +5 more
doaj   +1 more source

Serum cystatin C levels are negatively correlated with post-stroke cognitive dysfunction

open access: yesNeural Regeneration Research, 2020
Stroke is the leading cause of death and long-term disability worldwide, and cognitive impairment and dementia are major complications of ischemic stroke. Cystatin C (CysC) has been found to be a neuroprotective factor in animal studies.
Dao-Xia Guo   +14 more
doaj   +1 more source

Integrated Profiling of DEHP-Induced Hippocampal Neurotoxicity in Adult Female Rats Based on Transcriptomic and Neurobiological Analyses

open access: yesToxics
Di-2-ethylhexyl phthalate (DEHP) is a widely used plasticizer with recognized sex-dependent neurotoxicity. However, research on adult neurotoxicity is scarce, especially in females.
Jing Bai   +7 more
doaj   +1 more source

Salidroside alleviates ferroptosis of retinal ganglion cells in db/db mice

open access: yesFood Science and Human Wellness
Salidroside (Sal), is one of the important food supplements from the traditional Chinese medicine Integripetal rhodiola herb, encapsulating significant anti-oxidative stress, anti-ferroptosis, and neuroprotective attributes.
Wenqiang Liu   +16 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

GLCCI1 alleviates GRP78-initiated endoplasmic reticulum stress-induced apoptosis of retinal ganglion cells in diabetic retinopathy by upregulating and interacting with HSP90AB1

open access: yesScientific Reports
Retinal ganglion cells (RGCs) are among the first neurons to undergo apoptosis in diabetic retinopathy (DR), with their relationship to endoplasmic reticulum stress (ERS)-induced apoptosis still unclear. While glucocorticoid-induced transcript 1 (GLCCI1)
Jiayou Liu   +10 more
doaj   +1 more source

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