Results 41 to 50 of about 2,883,132 (337)
Postoperative Cognitive Dysfunction [PDF]
Deutsches Ärzteblatt international, 2014 Older patients in particular are vulnerable to memory disturbances and other types of cognitive impairment after surgical operations. In one study, roughly 12% of patients over age 60 had postoperative cognitive dysfunction (POCD) three months after surgery. This is an important issue in perioperative care as extensive surgery on older patients becomes
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Lesson of the week: Oxybutynin and cognitive dysfunction [PDF]
BMJ, 1997 Anticholinergic drugs have been used since the 19th century, when belladonna alkaloids were first given for treatment of Parkinson's disease. Their use declined because they were poorly tolerated, particularly by elderly patients. Recently, anticholinergic drugs have started to be used again for treating detrusor instability and hyperreflexia ...
J R Playfer +3 more
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SLC40A1 Mediates Ferroptosis and Cognitive Dysfunction in Type 1 Diabetes
Neuroscience, 2020 Cognitive dysfunction often accompanies diabetes. Both hypoglycemia and hyperglycemia cause cognitive dysfunctions. However, the underlying pathophysiology remains unclear.
Lijun Hao +6 more
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Mitochondrial Dysfunction as a Driver of Cognitive Impairment in Alzheimer’s Disease
International Journal of Molecular Sciences, 2021 Alzheimer’s disease (AD) is the most frequent cause of age-related neurodegeneration and cognitive impairment, and there are currently no broadly effective therapies.
Chanchal Sharma +4 more
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Frontiers in Microbiology, 2022 The pathogenesis of Hepatic Encephalopathy (HE) is complex and multifactorial. The development of metagenomics sequencing technology led to show the significant role of gut microbiota in the pathogenesis of cognitive dysfunction, which paved the way for ...
Bowen Yang +5 more
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CA3 Induces Apoptosis of Hepatocellular Carcinoma HepG2 Cells and Related Mechanism
Zhongliu Fangzhi Yanjiu, 2020 Objective To investigate the effect of CA3(CIL56) on the proliferation and apoptosis of hepatocellular carcinoma HepG2 cells and its mechanism. Methods HepG2 cells were cultured in vitro and treated with different concentrations of CA3 (0, 0.25, 0.5, 1.0,
ZHANG Shuwen +3 more
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Cognitive dysfunction in spinocerebellar ataxias [PDF]
Dementia & Neuropsychologia, 2009 Abstract Spinocerebellar ataxias (SCAs) comprise a heterogeneous group of complex neurodegenerative diseases, characterized by the presence of progressive cerebellar ataxia, associated or otherwise with ophthalmoplegia, pyramidal signs, extrapyramidal features, pigmentary retinopathy, peripheral neuropathy, cognitive dysfunction and dementia ...
Teive, Helio Afonso Ghizoni +1 more
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Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats
Aging, 2020 Postoperative cognitive dysfunction (POCD) is frequently observed in elderly patients following anesthesia, but its pathophysiological mechanisms have not been fully elucidated.
Yeru Chen +6 more
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Serum cystatin C levels are negatively correlated with post-stroke cognitive dysfunction
Neural Regeneration Research, 2020 Stroke is the leading cause of death and long-term disability worldwide, and cognitive impairment and dementia are major complications of ischemic stroke. Cystatin C (CysC) has been found to be a neuroprotective factor in animal studies.
Dao-Xia Guo +14 more
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Postoperative cognitive dysfunction—current research progress
Frontiers in Behavioral NeurosciencePostoperative cognitive dysfunction (POCD) commonly occurs after surgery, particularly in elderly individuals. It is characterized by a notable decline in cognitive performance, encompassing memory, attention, coordination, orientation, verbal fluency ...
Qi Zhao, Hui Wan, Hui Pan, Yiquan Xu
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