Results 61 to 70 of about 2,883,132 (337)

Diabetes and Cognitive Impairment: A Role for Glucotoxicity and Dopaminergic Dysfunction

International Journal of Molecular Sciences, 2021
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia, responsible for the onset of several long-term complications. Recent evidence suggests that cognitive dysfunction represents an emerging complication of DM, but the ...
F. Pignalosa, Antonella Desiderio, P. Mirra, C. Nigro, Giuseppe Perruolo, L. Ulianich, P. Formisano, F. Beguinot, C. Miele, R. Napoli, F. Fiory   +10 more
semanticscholar   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

Advanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

The Role of Neuroinflammation in Postoperative Cognitive Dysfunction: Moving From Hypothesis to Treatment

Frontiers in Psychiatry, 2019
Postoperative cognitive dysfunction (POCD) is a common complication of the surgical experience and is common in the elderly and patients with preexisting neurocognitive disorders.
Seyed A Safavynia, P. A. Goldstein
semanticscholar   +1 more source

Postoperative cognitive dysfunction: physiopathological aspects and clinical evidence [PDF]

The Moldovan Medical Journal, 2019
Background: Postoperative cognitive dysfunction (POCD) represents a decrease of cognitive abilities (memory, learning, concentration), which develops in the postoperative period after a variable amount of time (days or weeks).
Ghenadie Severin
doaj   +1 more source

Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay, E. Vichayanrat, F. Bremner, F. Valerio, R. Mackenzie, G. Chiaro, G. Ingle, P. McNamara, L. Watson, J. N. Panicker, M. P. Lunn, C. Mathias, V. Iodice   +12 more
wiley   +1 more source

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee   +7 more
wiley   +1 more source

Association of Thyroid Dysfunction With Cognitive Function

JAMA Internal Medicine, 2021
This individual participant data analysis assesses the cross-sectional and longitudinal associations of baseline thyroid dysfunction with cognitive function and dementia.
Nicolien A. van Vliet, D. van Heemst, O. Almeida, B. Åsvold, C. Aubert, J. Bae, L. Barnes, D. Bauer, G. Blauw, C. Brayne, A. Cappola, G. Ceresini, H. Comijs, J. Dartigues, J. Degryse, R. Dullaart, Marlise E. A. van Eersel, W. D. den Elzen, L. Ferrucci, H. Fink, L. Flicker, H. Grabe, Ji Won Han, C. Helmer, M. Huisman, M. Ikram, M. Imaizumi, R. D. de Jongh, J. Jukema, Ki Woong Kim, L. Kuller, O. Lopez, S. Mooijaart, J. Moon, E. Moutzouri, M. Nauck, J. Parle, R. Peeters, M. Samuels, C. Schmidt, U. Schminke, P. Slagboom, E. Stordal, B. Vaes, H. Völzke, R. Westendorp, M. Yamada, B. Yeap, N. Rodondi, J. Gussekloo, S. Trompet   +50 more
semanticscholar   +1 more source

Evaluation of Cognitive Dysfunction, Functional Independence and Depression Severity Changes during Rehabilitation in Patients after Cerebral Stroke

Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija, 2019
Research background. Cognitive impairment and depression are frequent residual consequences of stroke. They have a large impact on the quality of life and long-term prognosis.
Gintarė Mankė, Lina Varžaitytė, Aistė Berkutė, Erika Karkauskienė   +3 more
doaj   +1 more source

Translating a Preclinically Tested 15 Hz rTMS Protocol to Humans With Chronic Spinal Cord Injury: A Safety and Feasibility Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat, Mehmed B. Bayram, Morgan Paine, Janelle Carnahan, Jian Zhong, Xiaofei Guan, Guang H. Yue, Soha Saleh, Gail F. Forrest   +8 more
wiley   +1 more source

Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence.

Anesthesiology, 2019
WHAT WE ALREADY KNOW ABOUT THIS TOPIC Postoperative delirium and postoperative cognitive dysfunction both occur in a substantial number of older surgical patientsPostoperative delirium and postoperative cognitive dysfunction share risk factors and may co-
L. Daiello, Annie M. Racine, Ray Yun Gou, E. Marcantonio, Zhongcong Xie, L. Kunze, K. Vlassakov, S. Inouye, Richard N. Jones, D. Alsop, T. Travison, S. Arnold, Zara Cooper, B. Dickerson, T. Fong, E. Metzger, Á. Pascual-Leone, E. Schmitt, M. Shafi, Michele Cavallari, W. Dai, S. Dillon, J. Mcelhaney, C. Guttmann, Tammy T Hshieh, G. Kuchel, T. Libermann, L. Ngo, D. Press, J. Saczynski, S. Vasunilashorn, Margaret O’Connor, Eyal Y. Kimchi, J. Strauss, Bonnie Wong, M. Belkin, Douglas Ayres, M. Callery, F. Pomposelli, John Wright, M. Schermerhorn, Tatiana Abrantes, Asha Albuquerque, Sylvie E. Bertrand, Amanda K. Brown, A. Callahan, Madeline L. D’Aquila, Sarah L. Dowal, M. Fox, Jacqueline Gallagher, Rebecca Anna Gersten, Ariel Hodara, B. Helfand, Jennifer B. Inloes, J. Kettell, A. Kuczmarska, Jacqueline Nee, E. Nemeth, Lisa Ochsner, Kerry Palihnich, Katelyn R Parisi, Margaret R. Puelle, Sarah E. Rastegar, Margaret Vella, Guoquan Xu, Margaret Bryan, Jamey Guess, Dee Enghorn, A. Gross, Y. Gou, Daniel A. Habtemariam, Ilean Isaza, C. Kosar, C. Rockett, Douglas Tommet, Ted Gruen, Meg Ross, Katherine Tasker, James Gee, A. Kolanowski, M. Pisani, S. D. de Rooij, S. Rogers, S. Studenski, Y. Stern, A. Whittemore, G. Gottlieb, J. Orav, R. Sperling   +88 more
semanticscholar   +1 more source