Results 111 to 120 of about 711,556 (344)

Cognitive Flexibility in Cognitive Architecture

, 2020
The universal flexibility of biological systems needs to be reflected in cognitive architecture. In PRIMs, we attempt to achieve flexibility through a bottom-up approach. Using contextual learning, randomly firing of a set of instantiated primitive operators are gradually organized into context-sensitive operator firing sequences (i.e., primordial ...
Ji, Yang, van Rij, Jacolien, Taatgen, Niels   +2 more
openaire   +1 more source

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

Advanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu, Linling Li, Ting Luo, Gan Huang, Li Zhang, Benjamin Becker, Zhen Liang   +6 more
wiley   +1 more source

Homocysteine Mediates Cognitive Inflexibility Induced by Stress via Targeting PIN1

Brain Sciences
Background: Increasing evidence shows that HCY plays an important role in stress-induced cognitive dysfunction, and HCY significantly promotes the decline of cognitive function.
Xiaobing Chen, Ling Zhang, Bing Liu, Huafeng Dong, Shijia Zhang, Xue Wang, Zhaowei Sun, Fang Xie, Lingjia Qian, Yun Zhao   +9 more
doaj   +1 more source

Association Among Mothers’ Loneliness, Cognitive Flexibility, and Children’s Social Competence: Moderated Mediating Effect of Mothers’ Perceived Impact of COVID-19 on Daily Lives [PDF]

, 2022
Yea-Ji Hong
openalex   +1 more source

Vision and Flexibility in a Model of Cognitive Dissonance [PDF]

This paper explores the consequences of cognitive dissonance, coupled with time-inconsistent preferences, in an intertemporal decision problem with two distinct goals: acting decisively on early information (vision) and adjusting flexibly to late ...
Junichiro Ishida
core  

Reliable AI Platform for Monitoring BCI Caused Brain Injury and Providing Real‐Time Protection

Advanced Science, EarlyView.
BrainGuard enables real‐time and interpretable assessment of brain injury caused by brain computer interface (BCI). Using feature‐based Gaussian process (GP) emulators trained on limited biomechanical data, it efficiently predicts full‐field strain and constructs patient‐specific digital brain twins to support clinical diagnosis and long‐term BCI ...
Chufan He, Yanjun Ding, Timon Rabczuk, Chensen Ding   +3 more
wiley   +1 more source

The role of cognitive flexibility on higher level executive functions in mild cognitive impairment and healthy older adults

BMC Psychology
Background Mild Cognitive Impairment (MCI) is a preclinical condition between healthy and pathological aging, which is characterized by impairments in executive functions (EFs), including cognitive flexibility.
Ilaria Corbo, Giovanna Troisi, Giulia Marselli, Maria Casagrande   +3 more
doaj   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

The mediating role of cognitive flexibility in the relationship between social support and non-suicidal self-injury among adolescents: a multicenter cross-sectional study

Frontiers in Psychology
BackgroundNon-suicidal self-injury (NSSI) is a prevalent and concerning behavior among adolescents worldwide, particularly in China. This study aimed to investigate the relationships between social support, cognitive flexibility, and NSSI, and to examine
Chenchen Wang, Jiaqi Zheng, Guanghui Shen, Hong Chen, Xinwu Ye, Cheng-Han Li, Bin Wu   +6 more
doaj   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source