Results 151 to 160 of about 1,931,867 (302)

Modifiable Transdiagnostic Risk and Protective Factors as Potential CBT Augmentation Targets for Eating Disorders: An Updated Umbrella Review

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective A focus on transdiagnostic targets is one of the key strategies for developing effective, efficient, and scalable treatments for mental health conditions. We conducted an umbrella review of recent meta‐analyses (August 2022 to May 2026) to update our understanding of critical transdiagnostic intervention targets that could inform ...
Yuan Zhou   +2 more
wiley   +1 more source

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray   +2 more
wiley   +1 more source

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani   +11 more
wiley   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi   +6 more
wiley   +1 more source

Cognitive Impairment and Frailty

open access: yesJournal of the Indian Academy of Geriatrics, 2020
Astha Koolwal   +2 more
openaire   +2 more sources

Gender differentials in cognitive frailty among older adults in India: a multivariate decomposition approach

open access: yesScientific Reports
There has been an increasing focus on the interplay between physical frailty and cognitive impairment, as both conditions pose significant risks for life-threatening health complications and are receiving considerable attention in global geriatric health
Madhurima Sharma   +3 more
doaj   +1 more source

A shared frailty semi-parametric markov renewal model for travel and activity time-use pattern analysis [PDF]

open access: yes
This study investigates the influence of observed explanatory factors and unobserved random effect (heterogeneity) on episode durations of travel-activity chain.
Charles Raux, Iragaël Joly, Tai-Yu Ma
core  

Novel biomarkers of frailty in middle-aged and older females

open access: yes
The burden of frailty and its associated health complications, including cardiovascular disease, is becoming a critical health concern. Frailty is a multifactorial physiological decline that increases vulnerability to health stressors.
Boreskie, Kevin
core  

Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis

open access: yesEpilepsia, EarlyView.
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx   +192 more
wiley   +1 more source

The relationship between cognitive frailty, physical frailty and malnutrition in Turkish older adults

open access: yes
Objective: The aim of this study was to assess the relationship between cognitive and physical frailty and malnutrition in older adults. Methods: The study was cross-sectional and observational.
Isik, AHMET TURAN   +5 more
core   +1 more source

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