Results 31 to 40 of about 6,805,995 (208)

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Dual-site spatiotemporal and simultaneous inhibition on PIN1 via arsenic-retinoic albumin nanoparticles enables synergistic oncotherapy

Journal of Nanobiotechnology
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) is a master regulator of oncogenic signaling, uniquely catalyzing the isomerization of phosphorylated Ser/Thr-Pro motifs to drive malignant transformation, proliferation, and metastasis ...
Dayun Yang, Jianping Wang, Ruoru Liu, Jinfa Chen, Haiying Wen, Yu Li, Bo Lu, Zhao Guo, Daxiang Cui, Lee Jia, Haiyan Dong   +10 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Omega 3 fatty acids and cognitive health in older people. [PDF]

, 2012
Oily fish and other sources of long-chain n-3 polyunsaturated fatty acids (n-3 LCPs) have been proposed as protective against dementia and age related cognitive impairment.
Dangour, Alan, Uauy, Ricardo, Dangour, Alan D, Andreeva, Valentina, Andreeva, Valentina A, Sydenham, Emma   +5 more
core   +1 more source

Altered local intrinsic neural activity and molecular architecture in internet use disorders

Brain Research Bulletin
Background: Internet gaming disorder (IGD) is mainly characterized by its core dysfunction in higher-order brain cortices involved in inhibitory control, whose neurobiological basis remains unclear.
Longyao Ma, Qiuying Tao, Jinghan Dang, Jieping Sun, Xiaoyu Niu, Mengzhe Zhang, Yimeng Kang, Weijian Wang, Jingliang Cheng, Shaoqiang Han, Yong Zhang   +10 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Proposing a new focus for the study of natural and artificial cognitive systems [PDF]

, 2002
In the study of systems the function of the system is often a good hint to how it works. In the following paper I would like to suggest that in studying or modeling a cognitive system our pre-knowledge of their functions should be treated carefully.
Hershberg, Uri
core  

ChaC1-based drug screenings identify a synergistic lethal effect of auranofin and proteasome inhibitors in hepatocellular carcinoma cells

Cell Death Discovery
The γ-glutamylcyclotransferase, ChaC1, is an enzyme catalyzing glutathione (GSH) degradation. In this study, we performed a ChaC1-activity-directed pharmacological screening from FDA-approved drug library to identify GSH-sensitive agents, and found that ...
Cheng Yu, Jinyu Liu, Hejia Jian, Biwen Wen, Mingting Jiang, Binghui Zhang, Meiyan Lin, Junjin Lin, Zichan Dai, Chuan-Qi Zhong, Min Zheng   +10 more
doaj   +1 more source

What is the contribution of voluntary and reflex processes to sensorimotor control of balance?

Frontiers in Bioengineering and Biotechnology, 2022
The contribution to balance of spinal and transcortical processes including the long-latency reflex is well known. The control of balance has been modelled previously as a continuous, state feedback controller representing, long-latency reflexes. However,
Amel Cherif, Jacopo Zenzeri, Ian Loram
doaj   +1 more source