Results 61 to 70 of about 14,447,010 (307)

The role of neuroplasticity in enhancing learning and cognitive Health: A systematic review of applications, challenges, and health-oriented implications [PDF]

Payesh
Objective(s): Neuroplasticity refers to the brain’s ability to undergo functional and structural reorganization in response to experience and learning.
shabnam HamediFard, Mansoureh Farhangnia, Shadi Akbarian   +2 more
doaj  

Impact of the 2008 economic and financial crisis on child health : a systematic review [PDF]

, 2014
The aim of this study was to provide an overview of studies in which the impact of the 2008 economic crisis on child health was reported. Structured searches of PubMed, and ISI Web of Knowledge, were conducted.
Hein Raat, Hjern, A,, Raat, H, Faresjö, Tomas, Taylor-Robinson, David, Rajmil, Luis,, Louise Séguin, Raat, H. (Hein), Hjern, A, Nick Spencer, Fernandez de Sanmamed, Maria-Jose,, Rajmil, L. (Luis), Lucas, Patricia J., Seguin, Louise, de Sanmamed, María-José, Hjern, Anders, L. Kozyrskyj, Anita, de Sanmamed, MJF, David Taylor-Robinson, Faresjö, T. (Tomas), Raat, Hein,, Raat, Hein, Faresjö, Tomas,, Kozyrskyj, Anita, Fernandez, de Sanmamed M-J, Rajmil, Luis, Imti Choonara, Anita Kozyrskyj, Hjern, A. (Anders), Taylor-Robinson, D. (David), Tomas Faresjö, Choonara, I. (Imti), Lucas, Patricia J.,, Taylor-Robinson, David,, Choonara, Imti, Spencer, N, Spencer, Nick,, Rajmil, L, Choonara, I, Lucas, PJ, Fernandez de Sanmamed, Mar�a-Jos�, Faresj�, Tomas, Luis Rajmil, Kozyrskyj, AL, Séguin, L, Hjern, Anders,, on Behalf of the International Network for Research in Inequalities in Child Health (INRICH) On Behalf of the International Network for Research in Inequalities in Child Health (INRICH), Kozyrskyj, A. (Anita), Fernandez de Sanmamed, Maria-Jose, Patricia Lucas, Sanmamed, M.-J.F. (María-José Fernandez) de, Spencer, N. (Nick), Lucas, Patricia J, Seguin, Louise,, Choonara, Imti,, Taylor-Robinson, D, Kozyrskyj, A, María-José De Sanmamed, Lucas, Patricia, Anders Hjern, Spencer, Nick, L. Kozyrskyj, Anita,, Faresjö, T, Lucas, P.J. (Patricia), Kozyrskyj, Anita L., Séguin, L. (Louise), S�guin, Louise   +66 more
core   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Cognitive Abilities and Portfolio Choice [PDF]

We study the relation between cognitive ability and the decision to invest in stocks using the recent Survey of Health, Ageing and Retirement in Europe (SHARE).
Mario Padula, Tullio Jappelli, Dimitrios Christelis   +2 more
core   +2 more sources

Renewal through health research: HRCI position paper 2021

, 2021
On January 28th we launched our 2021 position paper: Renewal through health research. It lays out a series of critical health research actions to help create a post-Covid Ireland where healthcare is world-class and based on evidence. It calls for:
Health Research Charities Ireland, /
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Cognition and mental ill-health

European Psychiatry, 2010
Cognitive resources form the core mental health. It includes the general cognitive ability, flexibility and efficiency in learning and memory, as well as emotional intelligence, such as social skills and resilience in the face of stress. A range of psychosocial factors have been identified that promote successful adaptation to stress and can possibly ...
openaire   +2 more sources

Working across health services and academia: challenges and solutions for health research [PDF]

, 2019
This report presents the proceedings of an Irish Health Research Forum event held on November 13th 2019 on the challenges and potential solutions for researchers working across health services and academia. It also makes key recommendations for improving
Health Research Charities Ireland
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source