Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan +7 more
wiley +1 more source
Automated Extraction of Spatio-Semantic Graphs for Identifying Cognitive Impairment [PDF]
arXivExisting methods for analyzing linguistic content from picture descriptions for assessment of cognitive-linguistic impairment often overlook the participant's visual narrative path, which typically requires eye tracking to assess. Spatio-semantic graphs are a useful tool for analyzing this narrative path from transcripts alone, however they are limited
arxiv
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita +7 more
wiley +1 more source
Specificity of Cognitive Impairment in Neurological Disease: A Methodological Critique of Parkinson’s Disease [PDF]
, 1991 H. J. Sagar
openalex +1 more source
Mild cognitive impairment and subjective cognitive impairment [PDF]
Psychogeriatrics, 2008 Toshihisa Tanaka +4 more
openaire +2 more sources
Abnormal Synchronization Between Cortical Delta Power and Ripples in Hippocampal Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Discriminating between epileptogenic and physiological ripples in the hippocampus is important for identifying epileptogenic (EP) zones; however, distinguishing these ripples on the basis of their waveforms is difficult. We hypothesized that the nocturnal synchronization of hippocampal ripples and cortical delta power could be used ...
Takamitsu Iwata +10 more
wiley +1 more source
Cognitive Function in Multiple Sclerosis: A Subcortical Pattern of Neuropsychological Impairment? [PDF]
, 1991 Carlo Caltagirone +3 more
openalex +1 more source
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier +8 more
wiley +1 more source
Evaluating GPT's Capability in Identifying Stages of Cognitive Impairment from Electronic Health Data [PDF]
arXivIdentifying cognitive impairment within electronic health records (EHRs) is crucial not only for timely diagnoses but also for facilitating research. Information about cognitive impairment often exists within unstructured clinician notes in EHRs, but manual chart reviews are both time-consuming and error-prone.
arxiv