Results 151 to 160 of about 2,743,206 (258)

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

The UNC13A cryptic exon associates with cognitive impairment in Alzheimer's disease. [PDF]

Alzheimers Res Ther
Reeves MM, Aviles Carpintero S, Zanovello M, Jansen-West K, Yue M, Calliari A, Song Y, Dunmore J, Maroto Cidfuentes C, Ball S, Kachergus JM, Killeen HE, Rawlinson B, Engelberg-Cook E, DeTure M, Day GS, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Murray M, Thompson AE, Dickson DW, Fratta P, Petrucelli L, Josephs KA, Prudencio M.   +26 more
europepmc   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Chronic obstructive pulmonary disease and cognitive impairment in the Chinese elderly population: a large national survey

, 2016
Peng Yin,1,* Qingfeng Ma,2,* Limin Wang,1 Peng Lin,3 Mei Zhang,1 Shige Qi,1 Zhihui Wang1 1National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 2Department of Neurology, Xuanwu
Ma Q, Lin P, Yin P, Zhang M, Qi S, Wang Z, Wang L   +6 more
core  

The study of cognitive impairment in the elderly: Missteps, and opportunities missed. [PDF]

Indian J Psychiatry
Tharayil HM, Rai Y, Tekkalaki B, Andrade C.   +3 more
europepmc   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Role of NRF2 in Electroacupuncture's Effects on Postoperative Cognitive Impairment in Rats. [PDF]

Neuropsychiatr Dis Treat
Wang ZG, Cui DR, Gao Y, Yuan JG, Wang QJ, Chen YX.   +5 more
europepmc   +1 more source

Heart failure and cognitive impairment: Challenges and opportunities

, 2007
George A Heckman, Christopher J Patterson, Catherine Demers, Joye St.Onge, Irene D Turpie, Robert S McKelvieDepartment of Medicine, McMaster University, Hamilton, Ontario, CanadaAbstract: As populations age, heart failure (HF) is becoming increasingly ...
Catherine Demers, George A Heckman, Robert S McKelvie, Christopher J Patterson, Irene D Turpie, Joye St.Onge   +5 more
core  

Music and mild cognitive impairment: a scoping review. [PDF]

Gerontologist
Umeda LS, Dvorak AL, McElderry SA, Reed Thureson CA.   +3 more
europepmc   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source