Results 11 to 20 of about 616,085 (282)

Serum proinsulin levels as peripheral blood biomarkers in patients with cognitive impairment

Scientific Reports, 2023
Insulin has long been associated with dementia. Insulin affecting the clearance of amyloid-β peptide and phosphorylation of tau in the CNS. Proinsulin is a precursor of insulin and its elevated serum levels are associated with peripheral insulin ...
Abhinbhen W. Saraya, Chavit Tunvirachaisakul, Chanikarn Sonpee, Panticha Katasrila, Tanyares Sathaporn, Supatporn Tepmongkol, Sookjareon Tangwongchai   +6 more
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Vascular Cognitive Impairment [PDF]

Continuum, 2019
This article provides an overview of vascular cognitive impairment; discusses its epidemiology, subtypes, and associations with other neurodegenerative diseases; and reviews the diagnostic evaluation and management of these disorders.Cerebrovascular disease is a common cause of dementia and frequently coexists with neurodegenerative causes.
Dragos Catalin Jianu, Claudia Barsan
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Cross-sectional associations between short and mid-term blood pressure variability, cognition, and vascular stiffness in older adults

Cerebral Circulation - Cognition and Behavior, 2023
: Background: High blood pressure variability (BPV), particularly in older age, appears to be an independent risk factor for incident dementia. The current study aimed to investigate the association between different BPV measures (short- and mid-term ...
D.S. Gutteridge, P.J. Tully, A.E. Smith, T. Loetscher, H.A. Keage   +4 more
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Role of Exosomes in Brain Diseases

Frontiers in Cellular Neuroscience, 2021
Exosomes are a subset of extracellular vesicles that act as messengers to facilitate communication between cells. Non-coding RNAs, proteins, lipids, and microRNAs are delivered by the exosomes to target molecules (such as proteins, mRNAs, or DNA) of host
Nan Zhang, Fengling He, Ting Li, Jinzhi Chen, Liping Jiang, Liping Jiang, Xin-Ping Ouyang, Xin-Ping Ouyang, Lielian Zuo   +8 more
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Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Scientific Reports, 2021
Sleep deprivation (SD) is a common condition and an important health concern. In addition to metabolic and cardiovascular risks, SD associates with decreases in cognitive performance.
Tamas Csipo, Agnes Lipecz, Cameron Owens, Peter Mukli, Jonathan W. Perry, Stefano Tarantini, Priya Balasubramanian, Ádám Nyúl-Tóth, Valeriya Yabluchanska, Farzaneh A. Sorond, J. Mikhail Kellawan, György Purebl, William E. Sonntag, Anna Csiszar, Zoltan Ungvari, Andriy Yabluchanskiy   +15 more
doaj   +1 more source

The psychological impact of instrumental activities of daily living on people with simulated age-related macular degeneration

BJPsych Open, 2022
Background People with age-related macular degeneration (AMD) can report reduced mental health. There is also evidence that they struggle with daily tasks because of vision loss.
Anne Macnamara, Scott Coussens, Celia Chen, Victor R. Schinazi, Tobias Loetscher   +4 more
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Overlap between frontotemporal dementia and Alzheimer’s disease: case report

Geriatric Care, 2017
The frontal variant of Alzheimer’s disease (fv-AD) has been described in patients with prominent behavioral or executive dysfunctions. Subsequently, the spectrum of frontal variant Alzheimer’s disease has been enlarged to comprise patients with early ...
Maria Elena Di Battista, Maurizio Gallucci   +1 more
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Oxidative Stress and Cognitive Alterations Induced by Cancer Chemotherapy Drugs: A Scoping Review

Antioxidants, 2021
Cognitive impairment is one of the most deleterious effects of chemotherapy treatment in cancer patients, and this problem sometimes remains even after chemotherapy ends.
Omar Cauli
doaj   +1 more source

Vascular cognitive impairment [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2004
Alzheimer first describe vascular dementia (VaD) 111 years ago. Despite this, its history has been dogged by misconceptions and it is only in the past decade that our understanding has matured. For the greater part of the 20th century dementia was routinely attributed to arteriosclerosis and consequent chronic cerebral ischaemia.
openaire   +4 more sources

Mild Cognitive Impairment [PDF]

Continuum, 2013
The term mild cognitive impairment (MCI) is used to describe older subjects with demonstrable cognitive impairment who have not crossed the threshold for dementia. Because patients with MCI have an increased risk of developing dementia, especially Alzheimer disease (AD), there is significant interest in the clinical characterization of these subjects ...
Craig, Gordon, Daniel J, Martin
openaire   +4 more sources