Results 31 to 40 of about 2,743,206 (258)

Acid-Sensing Ion Channel 1/Calpain1 Activation Impedes Macrophage ATP-Binding Cassette Protein A1-Mediated Cholesterol Efflux Induced by Extracellular Acidification

Frontiers in Physiology, 2022
BackgroundExtracellular acidification is a common feature of atherosclerotic lesions, and such an acidic microenvironment impedes ATP-binding cassette transporter A1 (ABCA1)-mediated cholesterol efflux and promotes atherogenesis.
Yuan-Mei Wang, Mo-Ye Tan, Rong-Jie Zhang, Ming-Yue Qiu, You-Sheng Fu, Xue-Jiao Xie, Hong-Feng Gu   +6 more
doaj   +1 more source

Enriched environment attenuates hippocampal theta and gamma rhythms dysfunction in chronic cerebral hypoperfusion via improving imbalanced neural afferent levels

Frontiers in Cellular Neuroscience, 2023
Chronic cerebral hypoperfusion (CCH) is increasingly recognized as a common cognitive impairment-causing mechanism. However, no clinically effective drugs to treat cognitive impairment due to CCH have been identified.
Jiaxin Zheng, Sisi Peng, Lingling Cui, Xi Liu, Tian Li, Zhenyu Zhao, Yaqing Li, Yuan Hu, Miao Zhang, Linling Xu, JunJian Zhang   +10 more
doaj   +1 more source

Association of lower liver function with cognitive impairment in the Shenzhen ageing-related disorder cohort in China

Frontiers in Aging Neuroscience, 2022
BackgroundAccumulating evidence suggests that alterations in liver function may play an important role in the pathogenesis of Alzheimer’s disease (AD).
Kaiyu Wu, Kaiyu Wu, Chunyan Xu, Guozhen Qiu, Qiwen Guo, Chunchun Chen, Wei Liu, Jianjun Liu, Kangding Liu, Feiqi Zhu   +9 more
doaj   +1 more source

Late life depression with cognitive impairment: Evaluation and treatment [PDF]

, 2008
Consuelo H Wilkins1,2, Jose Mathews2, Yvette I Sheline21Department of Medicine (Division of Geriatrics and Nutritional Science); 2Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USAAbstract: Older adults with depression
Wilkins, Consuelo H, Yvette I Sheline, Sheline, Yvette I, Consuelo H Wilkins, Mathews, Jose, Jose Mathews, Consuelo Wilkins   +6 more
core   +1 more source

Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia

Frontiers in Aging, 2021
Growing life expectancy will contribute to the on-going shift towards a world population increasingly comprised of elderly individuals. This demographic shift is associated with a rising prevalence of age-related diseases, among all age-related ...
Priya Balasubramanian, Jordan Delfavero, Adam Nyul-Toth, Adam Nyul-Toth, Amber Tarantini, Rafal Gulej, Stefano Tarantini, Stefano Tarantini, Stefano Tarantini   +8 more
doaj   +1 more source

Kinematic analysis of handwriting movements in patients with Alzheimer's disease, mild cognitive impairment, depression and healthy subjects [PDF]

, 2003
A variety of studies have demonstrated that motor disorders, parkinsonism and extrapyramidal motor symptoms (EPMS) are common in patients with Alzheimer's disease (AD).
Hampel, H., Mergl, R., Hegerl, Ulrich, Möller, Hans-Jürgen, Burger, K., Schroter, A.   +5 more
core   +1 more source

Simulating Macular Degeneration to Investigate Activities of Daily Living: A Systematic Review

Frontiers in Neuroscience, 2021
Purpose: Investigating difficulties during activities of daily living is a fundamental first step for the development of vision-related intervention and rehabilitation strategies. One way to do this is through visual impairment simulations.
Anne Macnamara, Celia Chen, Victor R. Schinazi, Victor R. Schinazi, Dimitrios Saredakis, Tobias Loetscher   +5 more
doaj   +1 more source

Factors Associated With Virtual Reality Sickness in Head-Mounted Displays: A Systematic Review and Meta-Analysis

Frontiers in Human Neuroscience, 2020
The use of head-mounted displays (HMD) for virtual reality (VR) application-based purposes including therapy, rehabilitation, and training is increasing. Despite advancements in VR technologies, many users still experience sickness symptoms.
Dimitrios Saredakis, Ancret Szpak, Brandon Birckhead, Hannah A. D. Keage, Albert Rizzo, Tobias Loetscher   +5 more
doaj   +1 more source

The Effects of 3D Custom Foot Orthotics with Mechanical Plantar Stimulation in Older Individuals with Cognitive Impairment: A Pilot Study

Brain Sciences, 2022
Recent scientific evidence supports the idea that foot plantar stimulation increases the functional connectivity of brain regions involved in visuo-spatial and sensory-motor integration. In this before–after, non-randomised intervention study we assessed
Lorenzo Brognara, Mayra Alejandra Mafla-España, Isabel Gil-Molina, Yolanda Castillo-Verdejo, Omar Cauli   +4 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source