Results 11 to 20 of about 2,743,206 (258)

Role of Exosomes in Brain Diseases

Frontiers in Cellular Neuroscience, 2021
Exosomes are a subset of extracellular vesicles that act as messengers to facilitate communication between cells. Non-coding RNAs, proteins, lipids, and microRNAs are delivered by the exosomes to target molecules (such as proteins, mRNAs, or DNA) of host
Nan Zhang, Fengling He, Ting Li, Jinzhi Chen, Liping Jiang, Liping Jiang, Xin-Ping Ouyang, Xin-Ping Ouyang, Lielian Zuo   +8 more
doaj   +1 more source

Cognitive impairment in Parkinson's disease : is it a unified phenomenon? [PDF]

, 2005
Parkinson's disease (PD) has long been associated with dementia. This has been found to correlate with participant age, age at onset of PD and severity of PD.
Lowit, Anja, Howell, Peter, Brendel, Bettina   +2 more
core   +4 more sources

The psychological impact of instrumental activities of daily living on people with simulated age-related macular degeneration

BJPsych Open, 2022
Background People with age-related macular degeneration (AMD) can report reduced mental health. There is also evidence that they struggle with daily tasks because of vision loss.
Anne Macnamara, Scott Coussens, Celia Chen, Victor R. Schinazi, Tobias Loetscher   +4 more
doaj   +1 more source

Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Scientific Reports, 2021
Sleep deprivation (SD) is a common condition and an important health concern. In addition to metabolic and cardiovascular risks, SD associates with decreases in cognitive performance.
Tamas Csipo, Agnes Lipecz, Cameron Owens, Peter Mukli, Jonathan W. Perry, Stefano Tarantini, Priya Balasubramanian, Ádám Nyúl-Tóth, Valeriya Yabluchanska, Farzaneh A. Sorond, J. Mikhail Kellawan, György Purebl, William E. Sonntag, Anna Csiszar, Zoltan Ungvari, Andriy Yabluchanskiy   +15 more
doaj   +1 more source

Regional Differences in Effects of APOE epsilon 4 on Cognitive Impairment in Non-Demented Subjects [PDF]

, 2011
Item does not contain fulltextBACKGROUND: The APOE epsilon4 allele is a risk factor for Alzheimer's disease (AD). APOE epsilon4 is common in non-demented subjects with cognitive impairment.
Tsolaki, M, M. Tsolaki, L. Spiru, Spiru, L., Scheltens, P., Verhey, F. R. J., Ewers, M, B. Vellas, R.W. Jones, Elias-Sonnenschein, LS, L. Frölich, Wilcock, G, Kehoe, P. G., Almkvist, O, Kehoe, P.G., Froelich, Lutz, Nobili, F, Olde Rikkert, M., Hampel, H, Verhey, F.R.J., M. Olde Rikkert, P.G. Kehoe, L. Minthon, Frisoni, GB, Elias-Sonnenschein, L.S., Lund University., Frisoni, G. B., P. Scheltens, Wahlund, L. -O., Jones, RW, Frölich, L, Spiru, L, M. Ewers, Wilcock, G., F.R.J. Verhey, Norberg, J., Froelich, L., Schelthens, P, J. Norberg, Vellas, B, Almkvist, Ove, Riqaud, AS, Almkvist, Ove,, G. Wilcock, Frolich, L., Hampel, H., L.-O. Wahlund, Lenoir, H., Norberg, Joakim,, H. Hampel, Minthon, Lennart,, L.S. Elias-Sonnenschein, Jones, R.W., O. Almkvist, F. Nobili, Soininen, H., Graff, C., Norberg, J, Rikkert, M. Olde, Olde Rikkert, M, G.B. Frisoni, NOBILI, FLAVIO MARIANO, Kehoe, PG, Vellas, B., Minthon, Lennart, Frisoni, Giovanni B., Ewers, M., Jones, R. W., Minthon, L, Frisoni, G.B., Minthon, L., Jones, Roy W., Rigaud, A. -S, Wahlund, L.O., Rigaud, A.S., Graff, Caroline, Rigaud, A. S., Visser, P.J., Lenoir, H, Visser, PJ, Wahlund, Lars-Olof, Rigaud, AS, P.J. Visser, H. Lenoir, Almkvist, O., Nobili, F., Graff, C, Frölich, Lutz, Visser, P. J., Tsolaki, M., Elias-Sonnenschein, L. S., Wahlund, L. -O, C. Graff, Wahlund, L. O., Wahlund, LO, Verhey, FR, Scheltens, P, A.-S. Rigaud, Rikkert, Marcel Olde, Soininen, H, Rigaud, A. -S., Elias Sonnenschein, L. S., H. Soininen, Rikkert, M.O., Graff, C,, Froelich, L, Almkvist, O,   +106 more
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Overlap between frontotemporal dementia and Alzheimer’s disease: case report

Geriatric Care, 2017
The frontal variant of Alzheimer’s disease (fv-AD) has been described in patients with prominent behavioral or executive dysfunctions. Subsequently, the spectrum of frontal variant Alzheimer’s disease has been enlarged to comprise patients with early ...
Maria Elena Di Battista, Maurizio Gallucci   +1 more
doaj   +1 more source

Presence and significant determinants of cognitive impairment in a large sample of patients with Multiple Sclerosis [PDF]

, 2013
This work was supported by FISM - Fondazione Italiana Sclerosi Multipla (www.aism.it) - Cod. 2009/R/17.Objectives: To investigate the presence and the nature of cognitive impairment in a large sample of patients with Multiple Sclerosis (MS), and to ...
Cavallo, Marco, Picci, Rocco Luigi, Simona Malucchi, Furlan, Piermaria, Malucchi, Simona, Ostacoli, Luca, Johnston, Harriet, Bertolotto, Antonio, Rocco Luigi Picci, Francesco Scavelli, Carletto, Sara, Marco Cavallo, Cavallo, M, Borghi, Martina, Furlan, Pier Maria, Scavelli, Francesco, Martina Borghi, Pier Maria Furlan, Antonio Bertolotto, Harriet Johnston, Zuffranieri, Marco, Luca Ostacoli, Marco Zuffranieri, Sara Carletto   +23 more
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Oxidative Stress and Cognitive Alterations Induced by Cancer Chemotherapy Drugs: A Scoping Review

Antioxidants, 2021
Cognitive impairment is one of the most deleterious effects of chemotherapy treatment in cancer patients, and this problem sometimes remains even after chemotherapy ends.
Omar Cauli
doaj   +1 more source

Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study. [PDF]

, 2013
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion volume, brain atrophy, and cerebral microbleeds.
Lawrence, AJ, Barrick, Thomas R., Lawrence Andrew J., Barrick Thomas R., Andrew J Lawrence, Robin G Morris, MacKinnon, Andrew D., Hugh S. Markus, Thomas R Barrick, Bhavini Patel, Robin G. Morris, MacKinnon, AD, Bhavini Patel (405150), Barrick, TR, Philip M. Rich (405153), Markus, HS, Andrew D. MacKinnon, Rich, PM, Thomas R. Barrick (405154), Thomas R. Barrick, Hugh S Markus, Lawrence, Andrew J.; id_orcid, Patel, B, Andrew J. Lawrence, MacKinnon Andrew D., Rich, Philip M., Hugh S. Markus (366687), Andrew J. Lawrence (292444), Robin G. Morris (405151), Morris, RG, Patel Bhavini, Morris Robin G., Morris, Robin G., Andrew D MacKinnon, Rich Philip M., Patel, Bhavini, Philip M Rich, Andrew D. MacKinnon (405152), Markus Hugh S., Philip M. Rich, Markus, Hugh S.   +40 more
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Automatic detection of cognitive impairment with virtual reality [PDF]

, 2023
Cognitive impairment features in neuropsychiatric conditions and when undiagnosed can have a severe impact on the affected individual's safety and ability to perform daily tasks.
Celiktutan, O., Shergill, Sukhwinder S, Mannan, Farzana A, Porffy, Lilla A, Joyce, Dan W   +4 more
core   +1 more source