Results 51 to 60 of about 558,965 (135)

Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases

Analytical Cellular Pathology
Phospholipase D (PLD) is an enzyme that consists of six isoforms (PLD1–PLD6) and has been discovered in different organisms including bacteria, viruses, plants, and mammals.
Weiwei Zhang, Feiqi Zhu, Jie Zhu, Kangding Liu   +3 more
doaj   +1 more source

Associations of apolipoprotein E ε4 allele, regional cerebral blood flow, and serum liver function markers in patients with cognitive impairment

Frontiers in Neurology
IntroductionThe ε4 allele of the apolipoprotein E gene (APOE4) is expressed abundantly in both the brain and peripheral circulation as a genetic risk factor for Alzheimer’s disease (AD). Cerebral blood flow (CBF) dysfunction is an essential feature of AD,
Hao Wang, Lin Shi, Shimei Luo, Yishan Luo, Chunyan Xu, Guozhen Qiu, Qiwen Guo, Chunchun Chen, Taikun Lu, Kangding Liu, Feiqi Zhu   +10 more
doaj   +1 more source

Emerging applications of single-cell profiling in precision medicine of atherosclerosis

Journal of Translational Medicine
Atherosclerosis is a chronic, progressive, inflammatory disease that occurs in the arterial wall. Despite recent advancements in treatment aimed at improving efficacy and prolonging survival, atherosclerosis remains largely incurable.
Huiling Lin, Ming Zhang, Mi Hu, Yangkai Zhang, WeiWei Jiang, Wanying Tang, Yuxin Ouyang, Liping Jiang, Yali Mi, Zhi Chen, Pingping He, Guojun Zhao, Xinping Ouyang   +12 more
doaj   +1 more source

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

Redox Biology, 2019
Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function.
Stefano Tarantini, Marta Noa Valcarcel-Ares, Peter Toth, Andriy Yabluchanskiy, Zsuzsanna Tucsek, Tamas Kiss, Peter Hertelendy, Michael Kinter, Praveen Ballabh, Zoltán Süle, Eszter Farkas, Joseph A. Baur, David A. Sinclair, Anna Csiszar, Zoltan Ungvari   +14 more
doaj   +1 more source

Case Report: False vertebral artery stenosis: an rare phenomenon

Frontiers in Surgery
IntroductionTrans-radial access (TRA) has gained widespread adoption in neurointerventional procedures, particularly for cerebral angiography. The success of trans-radial cerebral angiography crucially relies on the proper formation of the simmons-2 ...
Yan Nao, Yan Nao, Yang Niao, Sun Dong, Sun Dong, Mei Bin, Mei Bin   +6 more
doaj   +1 more source

Analysis of the Association Between Symptoms of Inattention and Hyperactivity–Impulsivity and Substance Abuse in University Students

Psychiatry International
Background and objectives. Symptoms of Attention Deficit Hyperactivity Disorder (ADHD) are frequently present in university students, even without a clinical diagnosis, and may be aggravated by various factors.
Desirée Ibáñez-Tejedor, Omar Cauli
doaj   +1 more source

EBF1 is a potential biomarker for predicting progression from mild cognitive impairment to Alzheimer's disease: an in silico study

Frontiers in Aging Neuroscience
IntroductionThe prediction of progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) is an important clinical challenge. This study aimed to identify the independent risk factors and develop a nomogram model that can predict ...
Yanxiu Ju, Yanxiu Ju, Songtao Li, Songtao Li, Xiangyi Kong, Qing Zhao, Qing Zhao   +6 more
doaj   +1 more source

ReCOGnAIze app to detect vascular cognitive impairment and mild cognitive impairment. [PDF]

Alzheimers Dement
Mohammed AA, Vipin A, Leow YJ, Setiabudi E, Tan F, Agarwal H, Liau KX, Tanoto P, Liew SY, Qiu B, Sandhu GK, Wang JDJ, Aravindhan K, Kandiah N.   +13 more
europepmc   +1 more source

Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment. [PDF]

Front Aging Neurosci
Pyun JM, Han S, Park SW, Yeo NY, Park YH, Kim SY, Youn YC, Jang JW, and the Alzheimer’s Disease Neuroimaging Initiative.   +8 more
europepmc   +1 more source

Mild cognitive impairment and subjective cognitive impairment [PDF]

Psychogeriatrics, 2008
Masatoshi TAKEDA, Takashi MORIHARA, Masayasu OKOCHI, Golam SADIK, Toshihisa TANAKA   +4 more
openaire   +1 more source