Results 81 to 90 of about 641,525 (312)

Cognitive impairment in older people: its implications for future demand for services and costs [PDF]

, 2003
This study aimed to make projections, for the next 30 years, of future numbers of older people with cognitive impairment, their demand for long-term care services and the future costs of their care under a range of specified assumptions.

core  

Early Language Impairment as an Integral Part of the Cognitive Phenotype in Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Huntington's disease (HD) speech/language disorders have typically been attributed to motor and executive impairment due to striatal dysfunction. In‐depth study of linguistic skills and the role of extrastriatal structures in HD is scarce.
Arnau Puig‐Davi, Carla Franch‐Marti, Iñigo Ruiz‐Barrio, Frederic Sampedro, Jesus Perez‐Perez, Jordi A. Matias‐Guiu, Fernando Cuetos, Gonzalo Olmedo‐Saura, Laura Perez‐Carasol, Andrea Horta‐Barba, Ignacio Aracil‐Bolaños, Javier Pagonabarraga, Jaime Kulisevsky, Saul Martinez‐Horta   +13 more
wiley   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source

Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment

Frontiers in Neurology, 2020
Introduction: State of emergency caused by COVID-19 pandemic and subsequent lockdown hit Spain on 14th March 2020 and lasted until 21st June 2020. Social isolation measures were applied. Medical attention was focused on COVID-19.
Ainara Barguilla, Aida Fernández-Lebrero, Aida Fernández-Lebrero, Aida Fernández-Lebrero, Isabel Estragués-Gázquez, Greta García-Escobar, Irene Navalpotro-Gómez, Irene Navalpotro-Gómez, Irene Navalpotro-Gómez, Rosa María Manero, Rosa María Manero, Víctor Puente-Periz, Víctor Puente-Periz, Víctor Puente-Periz, Jaume Roquer, Albert Puig-Pijoan, Albert Puig-Pijoan, Albert Puig-Pijoan   +17 more
doaj   +1 more source

What Are the Key Points of Treatment for Cases of Mild Cognitive Impairment? Based on the Evaluation of Cognitive Function Tasks in the ADASJcog

Dementia and Geriatric Cognitive Disorders Extra, 2021
Background/Aims: The aims of this study were to identify the degree of atrophy of the hippocampus in image findings and which cognitive function items should be focused on when treating mild cognitive impairment.
Yoshihiko Yoshii, Akiko Takahashi, Miyuki Ishizawa   +2 more
doaj   +1 more source

‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure [PDF]

, 2015
The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. An association between cognitive impairment and heart failure is well described but our understanding of the relationship between the ...
Cannon, Jane A., McMurray, John J.V., Quinn, Terry J.   +2 more
core   +4 more sources

Separating Content from Speaker Identity in Speech for the Assessment of Cognitive Impairments [PDF]

arXiv, 2022
Deep speaker embeddings have been shown effective for assessing cognitive impairments aside from their original purpose of speaker verification. However, the research found that speaker embeddings encode speaker identity and an array of information, including speaker demographics, such as sex and age, and speech contents to an extent, which are known ...
arxiv  

Diagnostic Challenge in Frontal Variant Alzheimer's Disease With Low Amyloid‐β PET Retention

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diagnosing frontal variant Alzheimer's disease (fvAD) is difficult and could be even more difficult when amyloid‐beta (Aβ) PET retention is low. A 63‐year‐old woman presenting with a 3‐year history of apathy and memory impairment showed executive dysfunction, memory impairment, and severe bilateral frontotemporal atrophy on MRI.
Ryosuke Shimasaki, Masanori Kurihara, Kenji Ishibashi, Aya Midori Tokumaru, Kenji Ishii, Atsushi Iwata   +5 more
wiley   +1 more source

The importance of early immunotherapy in patients with faciobrachial dystonic seizures. [PDF]

, 2018
Faciobrachial dystonic seizures and limbic encephalitis closely associate with antibodies to leucine-rich glioma-inactivated 1 (LGI1). Here, we describe 103 consecutive patients with faciobrachial dystonic seizures and LGI1 antibodies to understand ...
Bi, Mian, Bien, Christian, Chu, Kon, Farooque, Pue, Gelfand, Jeffrey, Geschwind, Michael, Hirsch, Lawrence, Irani, Sarosh, Lang, Bethan, Leite, Maria, Makuch, Mateusz, Murchison, Andrew, Somerville, Ernest, Thompson, Julia, Vincent, Angela, Waters, Patrick   +15 more
core  

Cerebral small vessel disease, medial temporal lobe atrophy and cognitive status in patients with ischaemic stroke and transient ischaemic attack [PDF]

, 2017
BACKGROUND AND PURPOSE: Small vessel disease (SVD) and Alzheimer's disease (AD) are two common causes of cognitive impairment and dementia, traditionally considered as distinct processes.
Ali, M, Arba, F, Hankey, GJ, Inzitari, D, Lees, KR, Quinn, T, VISTA Collaboration,   +6 more
core   +2 more sources