Results 51 to 60 of about 2,531,453 (289)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Outlines, 2003 The purpose of this paper is to review the way in which cultural contributions to human nature have been treated within the field of cognitive science.
Michael Cole
doaj
#lockdown: Network-Enhanced Emotional Profiling in the Time of COVID-19
Big Data and Cognitive Computing, 2020 The COVID-19 pandemic forced countries all over the world to take unprecedented measures, like nationwide lockdowns. To adequately understand the emotional and social repercussions, a large-scale reconstruction of how people perceived these unexpected ...
Massimo Stella +2 more
doaj +1 more source
The functional form of value normalization in human reinforcement learning
eLife, 2023 Reinforcement learning research in humans and other species indicates that rewards are represented in a context-dependent manner. More specifically, reward representations seem to be normalized as a function of the value of the alternative options.
Sophie Bavard, Stefano Palminteri
doaj +1 more source
Leveling the Field: Talking Levels in Cognitive Science [PDF]
, 2016 Talk of levels is everywhere in cognitive science. Whether it is in terms of adjudicating longstanding debates or motivating foundational concepts, one cannot go far without hearing about the need to talk at different ‘levels’.
Brook, Andrew +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cognitive Science and Spirituality
Spirituality Studies, 2019 The study provides description and discussion on research in cognitive sciences in regard to spirituality. Meditation research shows that long-term meditators can sustain high amplitude brain oscillations and phase-synchrony during meditation ...
Michal Kutáš
doaj
Hume's Legacy: A Cognitive Science Perspective [PDF]
, 2018 Hume is an experimental philosopher who attempts to understand why we think, feel, and act as we do. But how should we evaluate the adequacy of his proposals?
Collier, Mark
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Knowledge and the Objection to Religious Belief from Cognitive Science [PDF]
, 2011 A large chorus of voices has grown around the claim that theistic belief is epistemically suspect since, as some cognitive scientists have hypothesized, such beliefs are a byproduct of cognitive mechanisms which evolved for rather different adaptive ...
Clark, Kelly James, Rabinowitz, Dani
core +3 more sources