Results 111 to 120 of about 2,345,325 (297)

Late‐midlife lifestyle and brain and cognitive changes in individuals on the AD versus non‐AD continuum

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION We investigated whether a composite measure of late‐midlife lifestyle was associated with (1) longitudinal brain changes and (2) cognitive changes when adjusting for these brain changes. METHODS We used linear mixed models to examine whether
Julie E. Oomens, Karly A. Cody, Lianlian Du, Erin M. Jonaitis, Rachel L. Studer, Nathaniel A. Chin, Sebastian Köhler, Pieter Jelle Visser, Stephanie J. B. Vos, Rebecca E. Langhough, Willemijn J. Jansen, Sterling C. Johnson   +11 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Trajectories of cognitive decline in different types of dementia

Psychological Medicine, 2014
Background.To investigate trajectories of cognitive decline in patients with different types of dementia compared to controls in a longitudinal study.Method.In 199 patients with Alzheimer's disease (AD), 10 with vascular dementia (VaD), 26 with dementia with Lewy bodies (DLB), 20 with behavioural variant frontotemporal dementia (bvFTD), 15 with ...
Smits, L.L., van Harten, A.C., Pijnenburg, Y.A.L., Koedam, E.L.G.E., Bouwman, F.H., Sistermans, N., Reuling, I.E.W., Prins, N.D., Lemstra, A.W., Scheltens, P., van der Flier, W.M.   +10 more
openaire   +4 more sources

Trajectories of cognitive ability and attitudes toward own aging in older adults: a conditional parallel latent growth model

BMC Geriatrics
Background Good cognitive function and positive attitudes toward own aging (ATOA) are important factors in promoting healthy aging. However, existing research has rarely explored the interrelationship between the developmental trajectories of cognitive ...
Songli Mei, Chengbin Zheng, Leilei Liang, Marhaba Kiyum, Junsong Fei, Tongshuang Yuan, Huimin Wang, Jiaying Gao, Xinli Lin   +8 more
doaj   +1 more source

Height and Cognitive Function among Older Europeans: Do People from "Tall" Countries Have Superior Cognitive Abilities? [PDF]

Previous research has found that height is correlated with cognitive functioning at older ages. It therefore makes sense to ask a related question: do people from countries where the average person is relatively tall have superior cognitive abilities on ...
Guven, Cahit, Lee, Wang-Sheng
core  

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Trajectories of normal cognitive aging.

Psychology and Aging, 2019
Although sensitive detection of pathological cognitive aging requires accurate information about the trajectory of normal cognitive aging, prior research has revealed inconsistent patterns of age-cognition relations with cross-sectional and longitudinal comparisons.
openaire   +2 more sources

Trajectories of cognitive function among people aged 45 years and older living with diabetes in China: Results from a nationally representative longitudinal study (2011~2018).

PLoS ONE
ObjectivesDiabetes is associated with decline of cognitive function. Exploring different trajectories of cognitive function occurring in people with diabetes is important to improved prognosis.
Shi Chen, Yuewei Ling, Faquan Zhou, Xu Qiao, Jan D Reinhardt   +4 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Exploring the association between multidimensional social isolation and heterogeneous cognitive trajectories among older adults: evidence from China

Frontiers in Public Health
ObjectiveThis study aims to elucidate the heterogeneous cognitive trajectories among older adults in China through a comprehensive, nationally representative longitudinal study.
Xinlong Xie, Yanxia Lyu, Yanxia Lyu, Fanfan Wu, Anpeng Zong, Zhiruo Zhuang, Aijun Xu, Aijun Xu   +7 more
doaj   +1 more source