Results 131 to 140 of about 2,345,325 (297)

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source

Longitudinal association between the weekend warrior physical activity pattern and cognitive function trajectories among middle-aged and older Chinese adults

Archives of Public Health
Background Cognitive decline is a major public health concern in aging societies, and physical activity (PA) is a key modifiable factor. Some individuals concentrate their PA into one or two days per week—the “weekend warrior” pattern—but its long-term ...
Meihan Liu, Youqiang Li
doaj   +1 more source

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

A general framework for reinforcement learning in cognitive architectures

Recent advancements in reinforcement learning (RL), particularly deep RL, show the capacity of this paradigm to perform varied and complex tasks. However, a series of exploration, generalization, and adaptation challenges hold RL back from operating in ...
Gudwin, Ricardo, Simões, Alexandre [UNESP], Yuji, Eduardo, Morais, Gustavo, Costa, Paula, Colombini, Esther   +5 more
core   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey, Jessica Fitzpatrick, Maria Dall'Era, Charmayne Dunlop‐Thomas, Courtney Hoge, S. Sam Lim, Patricia P. Katz, Jinoos Yazdany, Laura C. Plantinga   +8 more
wiley   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source

Trajectories of post-discharge cognitive function and associated risk factors in ICU survivors: a secondary analysis

Scientific Reports
Cognitive impairment is a significant concern among intensive care unit (ICU) survivors, yet post-discharge cognitive trajectories remain understudied.
Jiyeon Kang, Gee Young Suh, Chi Ryang Chung, Young-Shin Cho, Jiwon Hong   +4 more
doaj   +1 more source

Immune cells and the trajectories of depression, anxiety, and cognitive function among people with amyotrophic lateral sclerosis

Brain, Behavior, & Immunity - Health
Background: Amyotrophic lateral sclerosis (ALS) represents a complex syndrome characterized by motor, psychiatric, and cognitive symptoms, where associations between cellular immune features and non-motor manifestations remain unknown.
Yihan Hu, Elie Deeba, Ulf Kläppe, Linn Öijerstedt, John Andersson, Nicolas Ruffin, Fredrik Piehl, Caroline Ingre, Fang Fang, Christina Seitz   +9 more
doaj   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

Age-related trajectories of the development of social cognition

Frontiers in Psychology
Age-related trajectories of intrinsic functional connectivity (iFC), which represent the interconnections between discrete regions of the human brain, for processes related to social cognition (SC) provide evidence for social development through neural imaging and can guide clinical interventions when such development is atypical.
Zhi-Xiong Yan, Zhe He, Ling-Hui Jiang, Xia Zou   +3 more
openaire   +3 more sources