Results 71 to 80 of about 5,337,605 (357)

Pulse-compression ghost imaging lidar via coherent detection. [PDF]

open access: yesOptics Express, 2016
Ghost imaging (GI) lidar, as a novel remote sensing technique, has been receiving increasing interest in recent years. By combining pulse-compression technique and coherent detection with GI, we propose a new lidar system called pulse-compression GI ...
Chenjin Deng, Wenlin Gong, Shensheng Han
semanticscholar   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Novel Spectral-Efficient Coherent Radio-Over-Fiber Link With Linear Digital-Phase Demodulation

open access: yesIEEE Photonics Journal, 2020
In this paper, a novel spectral-efficient coherent radio-over-fiber (RoF) link with linear digital phase demodulation is proposed and experimentally demonstrated. At the transmitter, to make an efficient use of the optical power and spectra, an intensity-
Huixing Zhang   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

An Automatic Bias Voltage Control Technique for High-order Modulation Formats

open access: yesGuangtongxin yanjiu, 2022
In order to maintain the stability of the transmitter to ensure the quality of the output signal, we propose a novel technique of automatic bias control based on the pilot signal that can be used in high-order modulation formats.
Jia-qi HUANG   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Iterative amplitude/phase multiple-symbol differential sphere detection for DAPSK modulated transmissions

open access: yes, 2012
Differentially encoded and non-coherently detected transceivers exhibit a low complexity, since they dispense with complex channel estimation. Albeit this is achieved at the cost of requiring an increased transmit power, they are particularly beneficial,
Hari, K.V.S.   +5 more
core   +1 more source

Alamouti-Type STBC for Atmospheric Optical Communication Using Coherent Detection

open access: yesIEEE Photonics Journal, 2014
Alamouti-type space-time block coding is studied for optical wireless communication systems using coherent detection over atmospheric turbulence channels.
Mingbo Niu   +2 more
doaj   +1 more source

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