Results 81 to 90 of about 463,178 (329)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Distinguishing between optical coherent states with imperfect detection

, 2004
Several proposed techniques for distinguishing between optical coherent states are analyzed under a physically realistic model of photodetection. Quantum error probabilities are derived for the Kennedy receiver, the Dolinar receiver and the unitary ...
C. W. Helstrom, D. P. Bertsekas, H. P. Yuen, J. von Neumann, JM Geremia, K. Kraus, R. Monmose, T. S. Usuda, V. P. Belavkin   +8 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The effect of experience and of dots\u2019 density and duration on the detection of coherent motion in dogs [PDF]

, 2018
Knowledge about the mechanisms underlying canine vision is far from being exhaustive, especially that concerning post- retinal elaboration. One aspect that has received little attention is motion perception, and in spite of the common belief that dogs ...
Battaglini, Luca, Campana, Gianluca, Kanizs\ue1r, Orsolya, L\uf5oke, Miina, Marinelli, Lieta, Mongillo, Paolo   +5 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Coherent flow power doppler (CFPD): flow detection using spatial coherence beamforming [PDF]

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2015
Power Doppler imaging is a widely used method of flow detection for tissue perfusion monitoring, inflammatory hyperemia detection, deep vein thrombosis diagnosis, and other clinical applications. However, thermal noise and clutter limit its sensitivity and ability to detect slow flow.
You Leo, Li, Jeremy J, Dahl
openaire   +2 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Optimizing the Limit of Detection of Waveguide-Based Interferometric Biosensor Devices

Sensors, 2019
Waveguide-based photonic sensors provide a unique combination of high sensitivity, compact size and label-free, multiplexed operation. Interferometric configurations furthermore enable a simple, fixed-wavelength read-out making them particularly suitable
Jonas Leuermann, Adrián Fernández-Gavela, Antonia Torres-Cubillo, Sergio Postigo, Alejandro Sánchez-Postigo, Laura M. Lechuga, Robert Halir, Íñigo Molina-Fernández   +7 more
doaj   +1 more source

Testing single-photon wave packets by Hong-Ou-Mandel interference

, 2008
We discuss characterization of single-photon wave packets by measuring Hong-Ou-Mandel interference with a weak coherent pulse. A complete multimode calculation is presented and effects of multiphoton terms in the coherent field as well as the impact of ...
Banaszek, Konrad, Kolenderski, Piotr
core   +1 more source