Results 111 to 120 of about 14,877,607 (296)

Fracture Behaviour of Real Coarse Aggregate Distributed Concrete under Uniaxial Compressive Load Based on Cohesive Zone Model. [PDF]

Materials (Basel), 2021
Ying J, Guo J.
europepmc   +1 more source

Intracrystalline Void‐Mediated Toughening of Brittle Crystals in Quail Eggshells

Advanced Functional Materials, EarlyView.
In quail eggshells, the high density and disordered arrangement of intracrystalline voids inhibit lattice cleavage, suppress long‐range crack propagation, and promote deformation twinning and quasi‐plasticity, serving as an essential toughening motif. We show that these voids remain within a narrow subcritical size range and therefore predominantly do ...
Jingxiao Zhong, Qihang Wang, Andre E. Vellwock, Sinuhe Perea Puente, Tingting Zhu, Jia Hui Lim, Kadda Medjoubi, Sebastian Hoerl, Erika Griesshaber, Wolfgang W. Schmahl, Yannicke Dauphin, Emeline Raguin, Peter Werner, Francesco Stellacci, Michael V. Swain, Peter Fratzl, Shahrouz Amini   +16 more
wiley   +1 more source

Overcoming the cohesive zone limit in the modelling of composites delamination with TUBA cohesive elements

Composites Part A: Applied Science and Manufacturing
The wide adoption of composite structures in the aerospace industry requires reliable numerical methods to account for the effects of various damage mechanisms, including delamination. Cohesive elements are a versatile and physically representative way of modelling delamination.
Giorgio Tosti Balducci, Boyang Chen
openaire   +2 more sources

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Effect of Adhesive Thickness on Fatigue Disbonding Through a Cohesive Zone Modelling Approach

Engineering Proceedings
Adhesively bonded joints are crucial to the aeronautical industry, contributing to weight reduction and more sustainable flights. However, certifying these joints is still a topic of debate due to the lack of reliable inspection methods to determine ...
Johan Birnie, Maria Pia Falaschetti, Enrico Troiani   +2 more
doaj   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

Comparative Analysis of Phase-Field and Intrinsic Cohesive Zone Models for Fracture Simulations in Multiphase Materials with Interfaces: Investigation of the Influence of the Microstructure on the Fracture Properties

Applied Sciences
This study evaluates four widely used fracture simulation methods, comparing their computational expenses and implementation complexities within the finite element (FE) framework when employed on heterogeneous solids.
Rasoul Najafi Koopas, Shahed Rezaei, Natalie Rauter, Richard Ostwald, Rolf Lammering   +4 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

A finite-thickness rate-dependent cohesive zone model

Engineering Fracture Mechanics
This paper presents the formulation of an enriched cohesive element (CE) accounting for the confinement and the viscoelasticity of the adhesive layer under pure mode I solicitation. This formulation follows the structure of the hybrid approach, which combines the use of solid bulk elements (BEs) and CEs.
Planas Andrés, Mario, Paroissien, Eric, Lachaud, Frédéric, Gérard, Pierre   +3 more
openaire   +2 more sources