Results 171 to 180 of about 3,632,413 (364)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

A cohort analysis of pancreatic cancer, 1939–1969 [PDF]

, 1977
Melvin A. Benarde, William A. Weiss
openalex   +1 more source

Cohort Profile: The Lausanne cohort 65+ (Lc65+) [PDF]

International Journal of Epidemiology, 2021
Yves Henchoz, Juan Manuel Blanco, Sarah Fustinoni, David Nanchen, Christophe Büla, Laurence Seematter-Bagnoud, Armin von Gunten, Brigitte Santos-Eggimann   +7 more
openaire   +3 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Generating patient cohorts from electronic health records using two-step retrieval-augmented text-to-SQL generation [PDF]

arXiv
Clinical cohort definition is crucial for patient recruitment and observational studies, yet translating inclusion/exclusion criteria into SQL queries remains challenging and manual. We present an automated system utilizing large language models that combines criteria parsing, two-level retrieval augmented generation with specialized knowledge bases ...
arxiv  

Cohort Profile: The Doetinchem Cohort Study [PDF]

International Journal of Epidemiology, 2008
Henriette A. Smit, W. M. M. Verschuren, A. Blokstra, H. S. J. Picavet   +3 more
openaire   +3 more sources

Cohort Profile: The PELAGIE mother-child cohort

International Journal of Epidemiology
International ...
Warembourg, Charline, Monfort, Christine, Costet, Nathalie, Rouget, Florence, Pelé, Fabienne, Garlantézec, Ronan, Cordier, Sylvaine, Chevrier, Cécile   +7 more
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Screening mammography performance according to breast density: a comparison between radiologists versus standalone intelligence detection

Breast Cancer Research
Background Artificial intelligence (AI) algorithms for the independent assessment of screening mammograms have not been well established in a large screening cohort of Asian women.
Mi-ri Kwon, Yoosoo Chang, Soo-Youn Ham, Yoosun Cho, Eun Young Kim, Jeonggyu Kang, Eun Kyung Park, Ki Hwan Kim, Minjeong Kim, Tae Soo Kim, Hyeonsoo Lee, Ria Kwon, Ga-Young Lim, Hye Rin Choi, JunHyeok Choi, Shin Ho Kook, Seungho Ryu   +16 more
doaj   +1 more source

Methods for measuring school performance through cohort analysis [PDF]

, 1972
Jacques Légaré
openalex   +1 more source