Results 181 to 190 of about 3,374,176 (336)

Adverse effects of human leukocyte antigen-DR sharing on fertility: a cohort study in a human isolate

, 1985
Carole L. Ober, Walter W. Hauck, Donna D. Kostyu, Elizabeth O’Brien, Sherman Elias, Joe Leigh Simpson, Alice Martin   +6 more
openalex   +1 more source

Risk factors for hypertension in a national cohort study. [PDF]

, 1991
Earl S. Ford, Rebecca Cooper
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Measuring the impact of Educational Interventions on the Academic Performance of Academic Development Students in Second-Year Microeconomics [PDF]

This paper analyses the impact of educational interventions made in the first- and second-year microeconomics courses on academic development students’ final mark in the second-year course.
Leonard Smith, Vimal Ranchhod
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

A cohort mortality study of forestry workers exposed to phenoxy acid herbicides. [PDF]

, 1991
L M Green
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

A Cohort Study of Male Workers Exposed to Aromatic Amines : (Part 2) Latency of Urinary Tract Cancers

, 1983
Shigeru Yutani
openalex   +2 more sources

Herpes Zoster and Human Immunodeficiency Virus Infection: A Cohort Study of 101 Coinfected Patients [PDF]

, 1993
Anne-Marie Rogues, M. Dupon, J. Ladner, Jean‐Marie Ragnaud, Jean‐Luc Pellegrin, François Dabis   +5 more
openalex   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source