Results 61 to 70 of about 145,860 (305)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Degrees and composition of irreducible morphisms in coils
We characterize the finiteness of degrees of irreducible morphisms between indecomposable modules lying in coils of the Auslander–Reiten quivers of artin algebras.
Chaio, Claudia Alicia, Malicki, Piotr
core +1 more source
Structural specificity in coiled-coil interactions [PDF]
Coiled coils have a rich history in the field of protein design and engineering. Novel structures, such as the first seven-helix coiled coil, continue to provide surprises and insights. Large-scale datasets quantifying the influence of systematic mutations on coiled-coil stability are a valuable new asset to the area.
Gevorg, Grigoryan, Amy E, Keating
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Cyber–physical microgrid components fault prognosis using electromagnetic sensors
Higher operational requirements in cyber–physical microgrid system stress the electrical system and may push it to the edge of stability. Therefore, prognosis of the imminent failures is vital.
Tanushree Agarwal +5 more
doaj +1 more source
Influence of heat treatment on the microstructure of steel coils of a heating tube furnace
Transportation and refining of heavy metal-bearing oil are associated with the problems of localized destruction of metal structures and elements due to corrosion.
Vladimir Yu. Bazhin, Bashar Issa
doaj +1 more source
On-Surface Assembly of Coiled-Coil Heterodimers [PDF]
The coiled coil is a widespread protein motif responsible for directing the assembly of a wide range of protein complexes. To date, research has focused largely on the solution phase assembly of coiled-coil complexes. Here, we describe an investigation into coiled-coil heterodimer assembly where one of the peptides is immobilized directly onto a gold ...
Simon J, White +7 more
openaire +2 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Frequency response analysis is widely used as a method for the offline diagnosis of winding deformations in power transformers. To apply it to a working transformer, people need to determine how to inject the excitation signal and measure the response ...
Yangchun Cheng +7 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source

