Results 61 to 70 of about 145,860 (305)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Degrees and composition of irreducible morphisms in coils

open access: yes, 2019
We characterize the finiteness of degrees of irreducible morphisms between indecomposable modules lying in coils of the Auslander–Reiten quivers of artin algebras.
Chaio, Claudia Alicia, Malicki, Piotr
core   +1 more source

Structural specificity in coiled-coil interactions [PDF]

open access: yesCurrent Opinion in Structural Biology, 2008
Coiled coils have a rich history in the field of protein design and engineering. Novel structures, such as the first seven-helix coiled coil, continue to provide surprises and insights. Large-scale datasets quantifying the influence of systematic mutations on coiled-coil stability are a valuable new asset to the area.
Gevorg, Grigoryan, Amy E, Keating
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Cyber–physical microgrid components fault prognosis using electromagnetic sensors

open access: yesIET Cyber-Physical Systems, 2018
Higher operational requirements in cyber–physical microgrid system stress the electrical system and may push it to the edge of stability. Therefore, prognosis of the imminent failures is vital.
Tanushree Agarwal   +5 more
doaj   +1 more source

Influence of heat treatment on the microstructure of steel coils of a heating tube furnace

open access: yesЗаписки Горного института, 2021
Transportation and refining of heavy metal-bearing oil are associated with the problems of localized destruction of metal structures and elements due to corrosion.
Vladimir Yu. Bazhin, Bashar Issa
doaj   +1 more source

On-Surface Assembly of Coiled-Coil Heterodimers [PDF]

open access: yesLangmuir, 2012
The coiled coil is a widespread protein motif responsible for directing the assembly of a wide range of protein complexes. To date, research has focused largely on the solution phase assembly of coiled-coil complexes. Here, we describe an investigation into coiled-coil heterodimer assembly where one of the peptides is immobilized directly onto a gold ...
Simon J, White   +7 more
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Proposed methodology for online frequency response analysis based on magnetic coupling to detect winding deformations in transformers

open access: yesHigh Voltage, 2019
Frequency response analysis is widely used as a method for the offline diagnosis of winding deformations in power transformers. To apply it to a working transformer, people need to determine how to inject the excitation signal and measure the response ...
Yangchun Cheng   +7 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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