Results 61 to 70 of about 35,198 (261)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Abstract Leray–Schauder Type Alternatives and Extensions

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
We present a Leray–Schauder type alternative for a general class of maps. This enables us to obtain some Birkhoff–Kellogg type results and a Furi–Pera result.
O’Regan Donal
doaj   +1 more source

f-Contractive multivalued maps and coincidence points [PDF]

open access: yesJournal of Inequalities and Applications, 2013
The paper presents a coincidence point theorem and a common fixed point theorem for a single-valued mapping \(f:X\to X\) and a multi-valued one \(T:X\to 2^X\) using an \(f\)-contractive condition for \(T\). The contractive condition is given in terms of an \(\omega\)-distance in the sense of \textit{T. Suzuki} and \textit{W. Takahashi} [Topol.
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Leray–Schauder Alternatives for Maps Satisfying Countable Compactness Conditions

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
In this paper we present Leray–Schauder alternatives for a general class of Mönch type maps.
O’Regan Donal
doaj   +1 more source

Coincidence Point and Common Fixed Point in $C^*$-algebra Valued $\mathcal{R}$-metric Space using Picard-Jungck Iteration Process with Application in Graph Theory [PDF]

open access: yesSahand Communications in Mathematical Analysis
This paper focuses on establishing the existence and uniqueness of coincidence points and common fixed points in $C^*$-algebra valued $\mathcal{R}$-metric spaces, utilizing the Picard-Jungck iteration technique.
Astha Malhotra, Deepak Kumar
doaj   +1 more source

Coincidence points of principal bundles

open access: yesTopology and its Applications, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Coincidence Best Proximity Points of Proximal Berinde G-Contractions

open access: yesJournal of Mathematics
Recently, a concept of proximal Berinde contractions was introduced and applied to prove the existence of coincidence best proximity points in metric spaces. In this article, we established a new approach to show that these results can be obtained from a
Moosa Gabeleh, Jack Markin
doaj   +1 more source

Remarks on recent fixed point theorems for compatible maps

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1996
Following Gerald Jungck's formulation of compatibility of maps, several interesting fixed point theorems for such maps have been obtained, wherein at least one of the maps is continuous.
S. L. Singh, V. Chadha, S. N. Mishra
doaj   +1 more source

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