Results 51 to 60 of about 74,639 (286)

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source

The complexity of TB/HIV coinfection: an analysis of the social and health services context in the state of São Paulo, Brazil

Journal of Infection in Developing Countries, 2020
Introduction: Brazil is in the 19th position of priority countries for the control of TB/HIV coinfection, so we aimed to analyze the social and health services contexts that are associated with TB/HIV coinfection in São Paulo state.
Laura Terenciani Campoy, Luiz Henrique Arroyo, Antônio Vieira Ramos, Thais Zamboni Berra, Juliane Almeida Crispim, Mellina Yamamura, Ione Carvalho Pinto, Aline Aparecida Monroe, Alessandro Rolim Scholze, Rubia Laine de Paula Andrade, Kamila Anise Alexander, Regina Célia Fiorati, Giselle Lima de Freitas, Ricardo Alexandre Arcencio   +13 more
doaj   +1 more source

A coinfection model for HIV and HCV [PDF]

Biosystems, 2014
We study a mathematical model for the human immunodeficiency virus (HIV) and hepatites C virus (HCV) coinfection. The model predicts four distinct equilibria: the disease free, the HIV endemic, the HCV endemic, and the full endemic equilibria. The local and global stability of the disease free equilibrium was calculated for the full model and the HIV ...
Pinto, Carla M.A., Carvalho, Ana R.M.
openaire   +4 more sources

Prevalence of bacterial coinfection by study design.

, 2022
Prevalence of bacterial coinfection by study design.
Oula Nawaf Sindi (13184259), Faisal Salman Alshaikh (13184256), Brian Godman (487412), R. Andrew Seaton (9365924), Amanj Kurdi (8072462)   +4 more
core   +1 more source

Non–AIDS‐Defining Cancer Incidence in People With HIV in Milan, Italy, 2000–2023: Temporal Trends and Comparison With the General Population

International Journal of Cancer, EarlyView.
ABSTRACT People with HIV (PWH) are living longer, but contemporary data on non–AIDS‐defining cancers (NADCs) in Italy remain limited. We assessed incident cancers in a retrospective cohort of PWH in Milan, Italy, between January 2000 and December 2023. Follow‐up was grouped into 2000–2007, 2008–2015, and 2016–2023. Incidence rates (IRs) were calculated
Giacomo Pozza, Maddalena Matone, Letizia Oreni, Giorgia Carrozzo, Beatrice Caloni, Maria Vittoria Cossu, Davide Moschese, Anna Lisa Ridolfo, Cristina Gervasoni, Cinzia Fasola, Nicla La Verde, Davide Dalu, Spinello Antinori, Andrea Gori, Andrea Giacomelli   +14 more
wiley   +1 more source

Survey of both hepatitis B virus (HBsAg) and hepatitis C virus (HCV-Ab) coinfection among HIV positive patients

Virology Journal, 2009
Background HIV, HBVand HCV is major public health concerns. Because of shared routes of transmission, HIV-HCV coinfection and HIV-HBV coinfection are common. HIV-positive individuals are at risk of coinfection with HBV and HCV infections.
Pournia Yadollah, Ebrahimzade Farzad, Sheikhian Ali, Talei Gholamreza, Mohammadi Mohsen, Ghasemi Ehsan, Boroun Hadis   +6 more
doaj   +1 more source

Prevalence of malaria and Schistosoma mansoni coinfection in sub Saharan Africa: A systematic review and meta-analysis

Parasite Epidemiology and Control
Background: Malaria and schistosomiasis are two parasite illnesses that share transmission sites in distinct tropical climates. Malaria-schistosomiasis coinfection is widespread in Africa.
Wagaw Abebe, Birhanu Kassanew, Tadesse Misganaw, Agenagnew Ashagre, Getinet Kumie, Marye Nigatie, Yalewayker Gashaw, Ephrem Tamrat, Dagmawi Woldesenbet, Alembante Bazezew   +9 more
doaj   +1 more source

Epidemiology of coinfection with soil transmitted helminths and Plasmodium falciparum among school children in Bumula District in western Kenya

Parasites & Vectors, 2015
Background Many school children living in Africa are infected with plasmodia and helminth species and are consequently at risk of coinfection. However, the epidemiology of such coinfection and the implications of coinfection for children’s health remain ...
Stella Kepha, Fred Nuwaha, Birgit Nikolay, Paul Gichuki, Tansy Edwards, Elizabeth Allen, Sammy M. Njenga, Charles S. Mwandawiro, Simon J Brooker   +8 more
doaj   +1 more source

Impact of Cardiometabolic Risk Factors and Steatotic Liver Disease on Liver‐Related Outcomes in Patients With Chronic Hepatitis C After Curative Antiviral Therapy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Patients with chronic hepatitis C (CHC) frequently present with steatotic liver disease (SLD) and cardiometabolic risk factors (CMRFs). This study aimed to evaluate the impact of SLD and CMRFs on liver‐related outcomes (LROs) in CHC patients after HCV eradication.
Chung‐Feng Huang, Yi‐Hung Lin, Pei‐Chien Tsai, Ming‐Lun Yeh, Chih‐Wen Wang, Tyng‐Yuan Jang, Po‐Cheng Liang, Yu‐Ju Wei, Nai‐Jen Hou, Ming‐Yen Hsieh, Chao‐Kuan Huang, Tzu‐Chun Lin, Jee‐Fu Huang, Chia‐Yen Dai, Wan‐Long Chuang, Ming‐Lung Yu   +15 more
wiley   +1 more source

Age can be a Problem: Clostridium difficile and Cytomegalovirus Colitis Coinfection in an Immunocompetent 90-year-old Patient

International Journal of Gerontology, 2015
Clostridium difficile colitis and cytomegalovirus colitis coinfection has been documented in immunocompromised patients. However, this kind of coinfection has rarely been reported in immunocompetent patients.
Po-Hsun Chen, I-Ta Lu, Bor-Jen Lee, Chen-Yu Wang, Chien-Kuan Lee   +4 more
doaj   +1 more source